Results 31 to 40 of about 13,602,078 (332)

Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk [PDF]

, 2011
<p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p> <p><b>Methods and Results:</b> In the ...
Craen, A.J.M. de, Ford, I., Jukema, J.W., McInnes, I.B., Murray, H.M., Packard, C.J., PROSPER Study Grp, Sattar, N., Stott, D.J., Trompet, S., Welsh, P., Westendorp, R.G.J.   +11 more
core   +1 more source

The Regulatory Role of IL-10 in Neurodegenerative Diseases

Biomolecules, 2020
IL-10, an immunosuppressive cytokine, is considered an important anti-inflammatory modulator of glial activation, preventing inflammation-mediated neuronal degeneration under pathological conditions. In this narrative review, we summarize recent insights
C. Porro, A. Cianciulli, M. Panaro
semanticscholar   +1 more source

B-cell gene therapy for tolerance induction: host but not donor B cell derived IL-10 is necessary for tolerance

Frontiers in Microbiology, 2011
Genetically modified B cells are excellent tolerogenic APCs in multiple models of autoimmunity. However, the mechanisms of action are still not completely understood.
Yan eSu, Yan eSu, Ai-Hong eZhang, Ai-Hong eZhang, Nancy eNoben-Trauth, David William Scott, David William Scott   +6 more
doaj   +1 more source

IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression

Heliyon, 2020
Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic, induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in infected individuals that play a role in the ...
S. Dhar, Vishnupriyan K, S. Damodar, S. Gujar, Manjula Das   +4 more
semanticscholar   +1 more source

IL-10/IL-10 Receptor Signaling Regulates TIMP-1 Expression [PDF]

Cancer Biology & Therapy, 2002
An IL-10 responsive signal protein, termed IL-10E1, was cloned from human prostate cancer PC-3 ML cells based on its binding affinity for a novel enhancer element (i.e., HTE-1: 5’-CACGATGACTCATCACTGTTGAAAGACA-3’) of the Tissue Inhibitor of metalloproteinase-1 (TIMP-1) gene. Electrophoretic mobility shift assays (EMSAs) and enzyme linked immuno-sandwich
Min Wang, Youji Hu, Ischiro Shima, Mark E. Stearns   +3 more
openaire   +1 more source

IL-10 and IL-22 in Mucosal Immunity: Driving Protection and Pathology

Frontiers in Immunology, 2020
The barrier surfaces of the gastrointestinal tract are in constant contact with various microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the defense against pathogens.
Hua-Xing Wei, Baolong Wang, Bofeng Li
semanticscholar   +1 more source

Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6. [PDF]

, 2014
BackgroundConventional p38α inhibitors have limited efficacy in rheumatoid arthritis, possibly because p38 blockade suppresses the counter-regulatory mechanisms that limit inflammation.
Boyle, David L, Firestein, Gary S, Hammaker, Deepa, Topolewski, Katharyn   +3 more
core   +3 more sources

Changes in novel anti-infalmmatory cytokine concetration in the bood of endurance and race horses at different levels of training

Computational and Structural Biotechnology Journal, 2023
Several anti-inflammatory cytokines have been proposed as markers for exercise monitoring in humans such as the interleukin 1 receptor agonist (IL-ra), or interleukin 13 (IL-13).
Urszula Plisak, Jarosław Szczepaniak, Magdalena Żmigrodzka, Beata Giercuszkiewicz-Hecold, Olga Witkowska-Piłaszewicz   +4 more
doaj   +1 more source

Impact of Anti-Diabetic Treatments on Circulating Anti-Inflammatory Mediators (IL-10 and IL-13) in Type 2 Diabetes Patients [PDF]

Journal of Bioscience and Applied Research
Background and Objectives: Type 2 diabetes mellitus (T2DM) is a chronic condition marked by persistent hyperglycemia and low-grade inflammation, involving cytokines like IL-10 and IL-13.
Muhannad Shweash, Hatem Hadeed, Mahmood Mukhlif, Mohammed Shwaish, Haitham Abd   +4 more
doaj   +1 more source

Association of IL-9, IL-10, and IL-17 Cytokines With Hepatic Fibrosis in Human Schistosoma mansoni Infection

Frontiers in Immunology, 2021
This is a case series study to evaluate immunological markers associated with schistosomiasis advanced fibrosis, including 69 patients from an endemic area from the State of Sergipe and from the Hepatology Service of the University Hospital in Sergipe ...
Karine Garcez Schuster Franco, Karine Garcez Schuster Franco, Fabio Jorge Ramalho de Amorim, Fabio Jorge Ramalho de Amorim, Mário Adriano Santos, Carla Virgínia Vieira Rollemberg, Carla Virgínia Vieira Rollemberg, Fabricia Alvisi de Oliveira, Fabricia Alvisi de Oliveira, Alex Vianey Callado França, Alex Vianey Callado França, Camilla Natália Oliveira Santos, Camilla Natália Oliveira Santos, Lucas Sousa Magalhães, Lucas Sousa Magalhães, Rodrigo Anselmo Cazzaniga, Rodrigo Anselmo Cazzaniga, Frederico Santana de Lima, Luciana Benevides, Vanessa Carregaro, João Santana Silva, Hugo Leite de Farias Brito, Daniel Alvarenga Fernandes, Ângela Maria da Silva, Ângela Maria da Silva, Ângela Maria da Silva, Roque Pacheco de Almeida, Roque Pacheco de Almeida, Roque Pacheco de Almeida, Roque Pacheco de Almeida, Márcio Bezerra-Santos, Márcio Bezerra-Santos, Márcio Bezerra-Santos, Amélia Ribeiro de Jesus, Amélia Ribeiro de Jesus, Amélia Ribeiro de Jesus, Amélia Ribeiro de Jesus   +36 more
doaj   +1 more source