Results 151 to 160 of about 72,327,479 (284)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Lebrikizumab for atopic dermatitis in the elderly: A case series

JAAD Case Reports
Barbara Gruber, MD
doaj   +1 more source

Serum IgE, IL-4 and IL-13 Concentrations as Th2-Associated Biomarkers in Canine Giardiasis. [PDF]

Vet Sci
Durgut MK, Ok M, Iyigun SS, Akkus H, Sivrioglu G.   +4 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

IL-33 promotes efferocytosis by peritoneal macrophages by a mechanism associated with rapid granulocyte IL-13 production. [PDF]

Front Immunol
Legere SA, Nanjundappa RH, Meghnem D, Haidl ID, Edgar A, Hu Q, Légaré JF, Marshall JS.   +7 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Comment on: Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13. [PDF]

Pediatr Allergy Immunol
Yılmaz E, Özer NK, Topal E.
europepmc   +1 more source

IL-13.

Arerugi = [Allergy], 2017
openaire   +2 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13. [PDF]

Pediatr Allergy Immunol
Metwally NKA, Hashimoto S, Vijverberg SJH, Neerincx AH, Dierdorp BS, Dekker T, Haarman EG, Duitman JW, Gorenjak M, Toncheva AA, Harner S, Brandstetter S, Wolff C, Corcuera-Elosegui P, López-Fernández L, Sardón-Prado O, Pino-Yanes M, Potočnik U, Kabesch M, Kraneveld AD, Lutter R, Terheggen-Lagro SWJ, Abdel-Aziz MI, Maitland-van der Zee AH, SysPharmPediA Consortium.   +24 more
europepmc   +1 more source