IL-17-neutralizing antibody mitigates functional and structural changes in cigarette smoke-induced COPD model. [PDF]
Riani Moreira A +13 more
europepmc +1 more source
Secukinumab-induced Crohn's disease in a psoriasis patient: a case report highlighting paradoxical reactions to IL-17 inhibition. [PDF]
Dai H +6 more
europepmc +1 more source
The dual role of IL-17 in periodontitis regulating immunity and bone homeostasis. [PDF]
Tang Z, Jin L, Yang Y.
europepmc +1 more source
The role of IL-17-related signaling in myelomagenesis, disease prognosis/progression, and therapeutic approach-a scoping review. [PDF]
Kulig P +3 more
europepmc +1 more source
Association of vaginal IL-4, IL-6, IL-8, IL-17, IFN-γ, and dietary intake with IBD status and vaginal microbiota in pregnant individuals. [PDF]
Vargas-Robles D +14 more
europepmc +1 more source
Correction to: KRAS regulates IL-17 signal activity by affect the metastasis of osteosarcoma via an IL-17A-dependent manner. [PDF]
europepmc +1 more source
Related searches:
The cytokine IL-17 is now a target for an array of therapeutic monoclonal antibodies supposed to treat a variety of inflammatory diseases. The forerunner Secukinumab, an IL-17A neutralizing antibody, is meanwhile approved as first-line treatments for moderate-to-severe plaque psoriasis, and as second-line treatment for psoriatic arthritis and ...
Florian C, Kurschus, Sonja, Moos
openaire +2 more sources
A new family of cytokines, IL-17, has recently been defined that reveals a distinct ligand-receptor signaling system. Functional studies have provided evidence for its importance in the regulation of immune responses. Notably, 3 members, IL-17A, IL-17E (IL-25), and IL-17F, have been best characterized both in vitro and in vivo , and have been shown to ...
Mio, Kawaguchi +4 more
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Asthma is perceived as a heterogeneous disease with several clinical phenotypes and triggering factors. In general, cytokines from T-helper 2 cells are believed to be critical contributors of asthma. In recent years, IL-17, another T-helper lymphocyte-associated cytokine, has been put forward as another potentially important mediator of asthma ...
Elin, Silverpil, Anders, Lindén
openaire +2 more sources

