Results 241 to 250 of about 1,561,364 (334)

Extracellular Signal-Regulated Protein Kinase Mediates Interleukin 17 (IL-17)-Induced IL-8 Secretion inHelicobacter pylori-Infected Human Gastric Epithelial Cells

, 2004
Ladislava Sebkova, Antonia Pellicanò, Giovanni Monteleone, Barbara Grazioli, Giovanni Guarnieri, Maria Imeneo, Francesco Pallone, Francesco Luzza   +7 more
openalex   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Correction: Nafamostat mesilate attenuates renal fibrosis by suppressing the IL-17 signaling pathway. [PDF]

Front Pharmacol
Liao W, Fan R, Du Y, Wang H, Yang Y, Tian Y.   +5 more
europepmc   +1 more source

IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation [PDF]

, 2013
Seon-Yeong Lee, Seung‐Ki Kwok, Hye‐Jin Son, Jun‐Geol Ryu, Eun‐Kyung Kim, Hye‐Jwa Oh, Mi‐La Cho, Ji Hyeon Ju, Sung‐Hwan Park, Ho‐Youn Kim   +9 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Ly6G⁺ granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis. [PDF]

Elife
Sharma P, Sharma RD, Sarkar B, Panwar V, Das M, Singh LV, Jain N, Chaturvedi S, Mehra L, Rathee A, Sharma S, Foo S, Lee A, N PK, Das P, Viswanathan V, Kornfeld H, Howland SW, Babu S, Nandicoori VK, Singhal A, Kumar D.   +21 more
europepmc   +1 more source

IL-17 (IL-17A) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A natural nephroprotective adjuvant for cancer chemotherapy: Rosmarinic acid disrupts IL-17 A-Ferroptosis coupling in Ifosfamide-induced renal injury. [PDF]

Med Oncol
Süzen Celbek B, Şimşek H, Akaras N, Kandemir Ö, Kızıl HE, Mutlu H, Kandemir FM.   +6 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source