Results 231 to 240 of about 1,561,364 (334)

Structural basis for ACT1 oligomerization induced by IL-17 receptor hetero-tetramer. [PDF]

Nat Commun
Zhang H, Bai XC, Zhang X.
europepmc   +1 more source

HuR Is Required for IL-17–Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization

, 2013
Tomasz Herjan, Peng Yao, Qian Wen, Xiao Li, Caini Liu, Katarzyna Bulek, Dongxu Sun, Wen-Pin Yang, Jun Zhu, Aiqing He, Julie Carman, Serpil C. Erzurum, Howard D. Lipshitz, Paul L. Fox, Thomas A. Hamilton, Xiaoxia Li   +15 more
openalex   +2 more sources

Intermediate Monocytes in Acute Alcoholic Hepatitis Are Functionally Activated and Induce IL-17 Expression in CD4+ T Cells [PDF]

, 2019
Ashwin Dhanda, Emily L. Williams, Euan Yates, Philippa Lait, Lauren P. Schewitz‐Bowers, Doha Hegazy, Matthew Cramp, Peter L. Collins, Richard Lee   +8 more
openalex   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

IL-17 stimulates erythropoiesis in vivo by amplifying the response of erythroid progenitors to erythropoietin. [PDF]

PLoS Biol
Wu QC, Swaminathan A, Winward A, Lalonde L, Hwang Y, Littman N, Socolovsky M, Klein AM.   +7 more
europepmc   +1 more source

Decreased percentage of CD4+Foxp3+TGF-β+ and increased percentage of CD4+IL-17+ cells in bronchoalveolar lavage of asthmatics [PDF]

, 2014
Adam Barczyk, Władysław Pierzchała, Gaetano Caramori, Ryszard Wiaderkiewicz, Marcin M. Kamiński, Peter J. Barnes, Ian M. Adcock   +6 more
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Immunomodulatory hydrogel reprograms IL-17/NF-κB signaling to drive regeneration in diabetic wounds. [PDF]

Mater Today Bio
Xuan H, Liu Z, Lu K, Chen Y, Gu H, Li B, Sun J, Jin Y, Yang Y, Yuan H.   +9 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Role of IL-17 cytokines in tubal fibrosis and infertility due to salpingitis. [PDF]

Mol Biol Rep
Zhao J, Liu L.
europepmc   +1 more source