Results 211 to 220 of about 1,534,063 (244)
When IL-17 Blockade Backfires: Retropharyngeal Granuloma and Petrous Bone Osteonecrosis in a Patient with Psoriasis. [PDF]
Dermatol Pract ConceptCangialosi L +4 more
europepmc +1 more source
H7F ameliorates DSS-induced colitis through restoration of intestinal barrier function and inhibition of IL-17/NF-κb signaling. [PDF]
Front PharmacolZhou L +8 more
europepmc +1 more source
4-2 VHL-Recruiting PROTAC Inhibits the Growth and Migration of Triple Negative Breast Cancer Cells by Triggering Pyroptosis Through Fas-Mediated IL-17 Signaling. [PDF]
Drug Dev ResWang Q +5 more
europepmc +1 more source
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Journal of Dermatological Science, 2017
The cytokine IL-17 is now a target for an array of therapeutic monoclonal antibodies supposed to treat a variety of inflammatory diseases. The forerunner Secukinumab, an IL-17A neutralizing antibody, is meanwhile approved as first-line treatments for moderate-to-severe plaque psoriasis, and as second-line treatment for psoriatic arthritis and ...
Florian C, Kurschus, Sonja, Moos
openaire +2 more sources
The cytokine IL-17 is now a target for an array of therapeutic monoclonal antibodies supposed to treat a variety of inflammatory diseases. The forerunner Secukinumab, an IL-17A neutralizing antibody, is meanwhile approved as first-line treatments for moderate-to-severe plaque psoriasis, and as second-line treatment for psoriatic arthritis and ...
Florian C, Kurschus, Sonja, Moos
openaire +2 more sources
Expert Review of Clinical Immunology, 2019
Introduction: Psoriasis is a chronic, immune-mediated disease with significant associated comorbidities. Its pathogenesis is likely multifactorial, however, the interleukin-23/T helper 17 pathway has been identified as a critical axis in its pathogenesis.
Karen Ly +5 more
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Introduction: Psoriasis is a chronic, immune-mediated disease with significant associated comorbidities. Its pathogenesis is likely multifactorial, however, the interleukin-23/T helper 17 pathway has been identified as a critical axis in its pathogenesis.
Karen Ly +5 more
openaire +2 more sources
Expert Review of Respiratory Medicine, 2012
Asthma is perceived as a heterogeneous disease with several clinical phenotypes and triggering factors. In general, cytokines from T-helper 2 cells are believed to be critical contributors of asthma. In recent years, IL-17, another T-helper lymphocyte-associated cytokine, has been put forward as another potentially important mediator of asthma ...
Elin, Silverpil, Anders, Lindén
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Asthma is perceived as a heterogeneous disease with several clinical phenotypes and triggering factors. In general, cytokines from T-helper 2 cells are believed to be critical contributors of asthma. In recent years, IL-17, another T-helper lymphocyte-associated cytokine, has been put forward as another potentially important mediator of asthma ...
Elin, Silverpil, Anders, Lindén
openaire +2 more sources
Annual Review of Immunology, 2009
CD4+T cells, upon activation and expansion, develop into different T helper cell subsets with different cytokine profiles and distinct effector functions. Until recently, T cells were divided into Th1 or Th2 cells, depending on the cytokines they produce.
Thomas, Korn +3 more
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CD4+T cells, upon activation and expansion, develop into different T helper cell subsets with different cytokine profiles and distinct effector functions. Until recently, T cells were divided into Th1 or Th2 cells, depending on the cytokines they produce.
Thomas, Korn +3 more
openaire +2 more sources
Nature Reviews Immunology, 2019
IL-17-producing γδ T cells in the meningeal spaces support short-term spatial memory formation.
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IL-17-producing γδ T cells in the meningeal spaces support short-term spatial memory formation.
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Inflammation Research, 2022
The purpose of this review is to discuss the significance of IL-17 in SLE and the potential of IL-17-targeted therapy.Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs and tissues throughout the body. It is characterized by overactive B and T cells and loss of immune tolerance to autoantigens. Interleukin-17 (IL-17)
Yi, Yang +8 more
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The purpose of this review is to discuss the significance of IL-17 in SLE and the potential of IL-17-targeted therapy.Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs and tissues throughout the body. It is characterized by overactive B and T cells and loss of immune tolerance to autoantigens. Interleukin-17 (IL-17)
Yi, Yang +8 more
openaire +2 more sources