Results 211 to 220 of about 1,561,364 (334)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Baicalin alleviates mastitis in dairy cows by targeting IL-17RA to inhibit IL-17 signaling pathway activation. [PDF]

J Anim Sci Biotechnol
Feng R, Huang H, Ma Q, Gao W, Chen X, Yan X, Wang F, Zhang Q, Cao Y, Zhang H, Teng J, Ran X, Zhang Y, Fu S, Liu J, Liu X.   +15 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Interleukin-17 (IL-17) [PDF]

Science-Business eXchange, 2008
openaire   +3 more sources

Outcomes in Bimekizumab Treated Psoriasis Patients With Prior IL-17 Inhibitor Failure. [PDF]

J Psoriasis Psoriatic Arthritis
Song EJ, Pretorius P, Dasilva DR, Bunick CG, Liu C, Shahriari M.   +5 more
europepmc   +1 more source

Characterization of IL-17 and IL-17 receptor families in lampreys

Frontiers in Immunology, 2013
Cooper Max, Hirano Masayuki, Han Qifeng
openaire   +1 more source

IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice

, 2020
Monica Cappelletti, Samir Softic, Rohit Kohli, Christopher L. Karp, Senad Divanovic, R. Balfour Sartor, Leah M. Flick, Isaac T. W. Harley, Rachel Sheridan, Stavra A. Xanthakos, Traci E. Stankiewicz, Kris A. Steinbrecher, Daniel A. Giles   +12 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

IL-17 (IL-17A) [PDF]

Science-Business eXchange, 2010
openaire   +3 more sources

Imbalanced pro- and anti-Th17 responses (IL-17/granulocyte colony-stimulating factor) predict fatal outcome in 2009 pandemic influenza [PDF]

, 2011
Raquel Almansa, Lorenzo Socías, Paula Ramírez, Ignacio Martín‐Loeches, Jordi Vallés, Ana Loza, Jordi Rello, David J. Kelvin, Cristóbal León, Jesús Blanco, David Andaluz, Dariela Micheloud, Enrique Maraví, Raúl Ortíz de Lejarazu, Jesús F. Bermejo-Martín   +14 more
openalex   +1 more source