Results 261 to 270 of about 1,073,186 (289)

Multimodality Imaging of IL-18–Binding Protein-Fc Therapy of Experimental Lung Metastasis

Clinical Cancer Research, 2008
Abstract Purpose: Interleukin (IL)-18 plays important roles in cancer progression and metastasis. The goal of this study is to identify cell lines that are most sensitive to stand alone IL-18–binding protein (IL-18bp)-Fc treatment, to study the pharmacokinetics and tumor targeting efficiency of IL-18bp-Fc, and to evaluate the efficacy of
Qizhen, Cao, Weibo, Cai, Gang, Niu, Lina, He, Xiaoyuan, Chen   +4 more
openaire   +2 more sources

Interferon-γ Mediates Gene Expression of IL-18 Binding Protein in Nonleukocytic Cells

Biochemical and Biophysical Research Communications, 2000
Interleukin-18 (IL-18) binding protein is a soluble decoy receptor for IL-18 which efficiently antagonizes biological functions of IL-18 in vitro and in vivo. Since regulation of IL-18 activity likely contributes to the pathogenesis of inflammatory diseases as well as malignancies, we investigated gene expression of IL-18 binding protein (IL-18BP) in ...
H, Mühl, H, Kämpfer, M, Bosmann, S, Frank, H, Radeke, J, Pfeilschifter   +5 more
openaire   +2 more sources

[Secretion of IL-18 and IL-18 binding protein from splenocytes of ITP patients in vitro].

Zhongguo shi yan xue ye xue za zhi, 2012
This study was aimed to investigate the expression and clinical significance of IL-18, IL-18 binding protein (IL-18BP), IFN-γ and IL-4 secreted from splenocytes of patients with idiopathic thrombocytopenic purpura (ITP) in vitro. Spleen mononuclear cells (MNC) were prepared by using routine sterile method, and were cultured in RPMI 1640 complete medium
Ning-Ning, Shan, Xin, Wang, Yu-Jie, Jiang, Xiao-Hui, Sui, Ying, Li, Xin, Liu, Ming, Hou   +6 more
openaire   +1 more source

Differential synthesis and release of IL-18 and IL-18 Binding Protein from human platelets and their implications for HIV infection

Cytokine, 2017
IL-18 is a pro-inflammatory cytokine belonging to the IL-1 family and is produced in the body from macrophages, epithelial and dendritic cells, keratinocytes, adrenal cortex etc. The cytokine is produced as an inactive precursor that is cleaved inside cells into its mature form by activated caspase 1, which exists as an inactive precursor in human ...
Ossama, Allam, Suzanne, Samarani, Mohammad-Ali, Jenabian, Jean-Pierre, Routy, Cecile, Tremblay, Devendra, Amre, Ali, Ahmad   +6 more
openaire   +2 more sources

IL-18 and IL-18 Binding Protein Are Related to Disease Severity of Myelodysplastic Syndromes

Blood, 2022
Ting Wang, Ningyuan Ran, Nianbin Li, Mengtong Zang, Xin He, Qiulin Chen, Zonghong Shao, Rong Fu   +7 more
openaire   +1 more source

Blockade of IL-18 via long-acting IL-18 binding protein attenuates experimental diet-induced cholestatic disease

Journal of Hepatology, 2023
Dong-Hyun Kim, Jin Joo Park, Mi-Hyun Park, Kyungsun Lee, Jaekyu Han, Susan Chi, Moo Young Song, Seung Goo Kang, Sang-Hoon Cha, Yong-Hyun Han   +9 more
openaire   +1 more source

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Highly accurate protein structure prediction with AlphaFold

Nature, 2021
John M Jumper, Richard Evans, Alexander Pritzel   +2 more
exaly  

The protein corona from nanomedicine to environmental science

Nature Reviews Materials, 2023
Assist Prof Morteza Mahmoudi, Markita P Landry, Roxana Coreas   +2 more
exaly  

Evidence for the presence of interleukin (IL)-18, IL-18 receptor and IL-18 binding protein expression in the human endometrium.

Fertility and Sterility, 2001
O Yoshino, Y Osuga, T Yano, K Koga, O Tsutsumi, Y Taketani   +5 more
openaire   +1 more source