IL-22/IL-22R1 pathway enhances cholangiocarcinoma progression <i>via</i> ERK1/2 activation.
Zhou J +9 more
europepmc +1 more source
Correlation between serum IL-22 and IL-27 levels and vasculopathy in diabetic nephropathy patients. [PDF]
Hao F, Zhang S.
europepmc +1 more source
CLL crosstalk with naïve T cells enhances the differentiation of IL-22-producing T cells and CLL -cell survival. [PDF]
Ferrer G +11 more
europepmc +1 more source
Genetically Engineered Probiotic Limosilactobacillus reuteri Releasing IL-22 (LR-IL-22) Modifies the Tumor Microenvironment, Enabling Irradiation in Ovarian Cancer. [PDF]
Hamade DF +14 more
europepmc +1 more source
Diagnostic and prognostic biomarkers in autoimmune hepatitis-associated cirrhosis: insights into TBil, CD38, IL-22, TSP-1, GAL-3, and Cyc-C. [PDF]
Shi J, Fu J, He C, Shen J.
europepmc +1 more source
IL-22 regulates MASTL expression in intestinal epithelial cells.
Pravoverov K +7 more
europepmc +1 more source
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Human IL-22 binding protein isoforms act as a rheostat for IL-22 signaling
Science Signaling, 2016Two soluble binding proteins that differ in inhibitory ability and abundance fine-tune signaling by the cytokine interleukin-22.
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Effects of IL-22 on cardiovascular diseases
International Immunopharmacology, 2020Interleukin-22 (IL-22), which belongs to the IL-10 family, is an alpha helix cytokine specifically produced by many lymphocytes, such as Th1, Th17, Th22, ILCs, CD4+ and CD8+ T cells. In recent years, more and more studies have demonstrated that IL-22 has an interesting relationship with various cardiovascular diseases, including myocarditis, myocardial
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IL-22 Signaling in the Tumor Microenvironment
2021Interleukin (IL)-22 belongs to the IL-10 cytokine family which performs biological functions by binding to heterodimer receptors comprising a type 1 receptor chain (R1) and a type 2 receptor chain (R2). IL-22 is mainly derived from CD4+ helper T cells, CD8+ cytotoxic T cells, innate lymphocytes, and natural killer T cells.
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