Results 141 to 150 of about 1,543,952 (322)

Th17, intestinal microbiota and the abnormal immune response in the pathogenesis of celiac disease [PDF]

open access: yes, 2015
Celiac disease (CD) is an autoimmune enteropathy induced by the ingestion of gluten in genetically predisposed individuals who carry the HLA-DQ2 or -DQ8 alleles.
Cicerone, Clelia   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

TSLP, IL-33, and IL-25: Not just for allergy and helminth infection. [PDF]

open access: yesJ Allergy Clin Immunol, 2022
Stanbery AG   +4 more
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Lung-derived innate cytokines: new epigenetic targets of allergen-specific sublingual immunotherapy [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2016
Objective(s):Sublingual allergen-specific immunotherapy is a safe and effective method for treatment of IgE-mediated respiratory allergies; however, the underlying mechanisms are not fully understood.
Abbas Pishdadian   +6 more
doaj  

The IL-25/ILC2 axis promotes lung cancer with a concomitant accumulation of immune-suppressive cells in tumors in humans and mice. [PDF]

open access: yesFront Immunol, 2023
Bahhar I   +7 more
europepmc   +1 more source

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