Results 71 to 80 of about 1,155,232 (268)

IL-31 a TH2 Cytokine Involved in Immunity and Inflammation

International Journal of Immunopathology and Pharmacology, 2010
Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor.
CASTELLANI, Maria Luisa, FELACO, PAOLO, Galzio R. J., TRIPODI, Domenico, TONIATO, ELENA, De Lutiis M. A., FULCHERI, Mario, Caraffa A., Antinolfi P., Tetè S., FELACO, Mario, CONTI, FIORELLA, Pandolfi F., Theoharides T. C., Shaik Dasthagirisaheb Y. B.   +14 more
openaire   +6 more sources

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Oncostatin M suppresses IL31RA expression in dorsal root ganglia and interleukin-31-induced itching

Frontiers in Immunology, 2023
BackgroundAtopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intermittent itchy rash. Type 2 inflammatory cytokines such as interleukin (IL)-4, IL-13, and IL-31 are strongly implicated in AD pathogenesis.
Masataka Suehiro, Tomofumi Numata, Ryo Saito, Nozomi Yanagida, Chie Ishikawa, Kazue Uchida, Tomoko Kawaguchi, Yuhki Yanase, Yozo Ishiuji, John McGrath, Akio Tanaka   +10 more
doaj   +1 more source

Opinion Poll: Small Business Owners Hiring, but Struggle to Find Qualified Workers [PDF]

, 2014
Findings from a new public opinion poll show that 56 percent of small employers have difficulty finding candidates with the right kind of job experience and 54 percent say they struggle to identify candidates with the right education, skills or training.

core  

A 3D radiative transfer framework: X. Arbitrary Velocity Fields in the Co-moving Frame

, 2012
3-D astrophysical atmospheres will have random velocity fields. We seek to combine the methods we have developed for solving the 1-D problem with arbitrary flows to those that we have developed for solving the fully 3-D relativistic radiative transfer ...
Baron, E., Chen, Bin, Hauschildt, Peter H., Knop, Sebastian   +3 more
core   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis [PDF]

, 2016
Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant ...
Bai, Yun, Bandara, Geethani, Beaven, Michael A., Desai, Avanti, Kim, Do-Kyun, Komarow, Hirsh, Kulinski, Joseph M., Metcalfe, Dean D., Olivera, Ana, Prussin, Calman, Schwartz, Lawrence B.   +10 more
core   +5 more sources

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients—Final Results of the Phase II Feasibility Study TEDDI

Pediatric Blood &Cancer, EarlyView.
Abstract Introduction The TEDDI trial tested the feasibility and reproducibility of deep‐inspiration breath‐hold (DIBH) in pediatric patients referred for radiotherapy. This report presents final results, including patient‐reported outcomes (PRO) and dosimetric comparison of DIBH and free‐breathing (FB).
Daniella Elisabet Østergaard, Anni Young Lundgaard, Laura Ann Rechner, Danijela Dejanovic, Hanne Krogh Rose, Jolanta Hansen, Leila Vaalavirta, Miia Mokka, Marianne Aznar, Peder Skov Wehner, Lisa Lyngsie Hjalgrim, Maja Vestmø Maraldo   +11 more
wiley   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Activation of eosinophils interacting with dermal fibroblasts by pruritogenic cytokine IL-31 and alarmin IL-33: implications in atopic dermatitis. [PDF]

PLoS ONE, 2012
BACKGROUND:IL-31 is a pruritogenic cytokine, and IL-33 is an alarmin for damaging inflammation. They together relate to the pathogenesis of atopic dermatitis (AD).
Chun-Kwok Wong, Karen Ming-Lam Leung, Huai-Na Qiu, Joyce Yin-Sau Chow, Angela On Kei Choi, Christopher Wai-Kei Lam   +5 more
doaj   +1 more source