Results 51 to 60 of about 1,058,192 (273)
IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis [PDF]
Journal of Investigative Dermatology, 2020 Psoriasis is an immune-mediated skin disorder associated with severe systemic co-morbidities. While IL-36 is a key disease driver, the pathogenic role of this cytokine has mainly been investigated in skin. Thus, its effects on systemic immunity and extra-cutaneous disease manifestations remain poorly understood.
Marika Catapano +13 more
openaire +8 more sources
Study the Effect of Interleukin36 Gamma and AMH in Iraqi Women with PCOS
Al-Mustansiriyah Journal of Science, 2018 Polycystic ovary syndrome (PCOS) is one of the most common female endocrine disorders and affect approximately (5-10) % of women of reproductive age. Anti-Müllerian hormone (AMH) is a homodimeric glycoprotein, a member of the transforming growth factor-β
Wafa R. AlFatlawi
doaj +1 more source
Interleukin-36 in Infectious and Inflammatory Skin Diseases
Frontiers in Immunology, 2019 Interleukin-36 (IL-36) comprises to a cytokine family consisting of four isoforms IL-36α, IL-36β, IL-36γ, and IL-36 receptor antagonist (IL-36 Ra). These IL-36 cytokines, in turn, belong to the IL-1 superfamily.
Anna-Lena Buhl, Joerg Wenzel
doaj +1 more source
Severe Acute Generalized Exanthematous Pustulosis Successfully Treated by Spesolimab
Acta Dermato-Venereologicais missing (Short communication)
Giuseppe Russo +6 more
doaj +1 more source
Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome. [PDF]
, 2015 The aim of this study was to investigate the expression of the interleukin (IL)-36 axis in patients with primary Sjögren's syndrome (pSS). Blood and minor labial salivary glands (MSG) biopsies were obtained from 35 pSS and 20 non-Sjögren's syndrome ...
Accardo Palumbo A +11 more
core +2 more sources
Cytokine, 2021 Alarmins ((IL-25, IL-33 and thymic stromal lymphopoietin (TSLP)) are known to promote Th2 inflammation and could be associated with eosinophilic airway infiltration. They may also play a role in airway remodeling in chronic airway obstructive diseases such as asthma and chronic obstructive pulmonary disease (COPD). IL-23 and IL-36 were shown to mediate
Moermans, Catherine +7 more
openaire +2 more sources
IL-36 Receptor Antagonist with Special Emphasis on IL-38
International Journal of Immunopathology and Pharmacology, 2013 IL-36 is another family member of IL-1 and induces the production of proinflammatory cytokines and activates MAPK and NFκB pathways. IL-36 is a common mediator of innate and adaptive immune response and is inhibited by IL-36 receptor antagonist (RA). IL-36RA acts on IL-36 receptor ligand which exerts proinflammatory effect in vivo and in vitro.
Y. Shaik +15 more
openaire +5 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
, 2020 Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima +18 more
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi +20 more
wiley +1 more source