Results 41 to 50 of about 5,139,608 (255)
Вопросы современной педиатрии, 2021 Background. This article discusses issues of diagnosis and management of pustular psoriasis in a child associated with recurrent dermatomycosis, immunopathogenetic mechanisms of pustular psoriasis, its course and prognosis. Clinical Case Description. The
Andrey L. Bakulev +2 more
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Effect of YangxueJiedu Decoction on the expression levels of IL-36 in psoriasis-like lesions in mice
Pifu-xingbing zhenliaoxue zazhi, 2021 Objective: To explore the effect of YangxueJiedu decoction on IL-36 expression in a mouse model of imiquimod-induced psoriasis-like lesions. Methods: Eighteen mice were randomly divided into the control, model and experimental groups, with 6 mice per ...
Qi ZHANG +3 more
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Cytokine, 2023 The IL-36 cytokines are a recently described subset of the IL-1 family of cytokines, and have been shown to play a role in the pathogenesis of respiratory diseases such as asthma and COPD. Given the common aetiological links between COPD and lung cancer development, as well as the involvement of other IL-1 family members in lung tumorigenesis, the aim ...
Kevin James, Baker +6 more
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Structural Basis of IL-1 Family Cytokine Signaling
Frontiers in Immunology, 2019 Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.
James K. Fields +6 more
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Rationale for IL-36 receptor antibodies in ulcerative colitis [PDF]
Expert Opinion on Biological Therapy, 2019 Ulcerative colitis (UC) is a chronically relapsing inflammatory disease of the colonic mucosa. It affects genetically susceptible hosts that are influenced by environmental factors and contribution...
Clemens, Neufert +2 more
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IL-36 Signaling in the Tumor Microenvironment
, 2020 The ability of the immune system to prevent or control the growth of tumor cells is critically dependent on inflammatory processes that lead to the activation, expansion, and recruitment of antitumor effector cells into the tumor microenvironment (TME).
Manoj, Chelvanambi +2 more
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Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
International Journal of COPD, 2022 Nikolaos Pournaras,1,2 Anders Andersson,3,4 Melissa A Kovach,1 Médea Padra,5 Karlhans F Che,1,2 Bettina Brundin,1 Shigemi Yoshihara,6 Steven Bozinovski,7 Sara K Lindén,5 Per-Anders Jansson,8 Magnus C Sköld,2,9 Ingemar Qvarfordt,3,8 Anders Lindén1,2 ...
Pournaras N +12 more
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Clinical, Cosmetic and Investigational Dermatology, 2023 Jason E Hawkes,1,* Dale V Reisner,2 Tina Bhutani3,* 1Department of Dermatology, University of California at Davis, Sacramento, CA, USA; 2Patient Author, Yankton, SD, USA; 3Psoriasis and Skin Treatment Center, Department of Dermatology, University
Hawkes JE, Reisner DV, Bhutani T
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Cell Reports, 2020 Summary: Epithelial tissues represent vital interfaces between organisms and their environment. As they are constantly exposed to harmful pathogens, innocuous commensals, and environmental microbes, it is essential they sense and elicit appropriate ...
Thomas Macleod +11 more
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A review of IL-36: an emerging therapeutic target for inflammatory dermatoses
Journal of Dermatological Treatment, 2022 IL-36 cytokines are members of the IL-1 superfamily. Increasing evidence in the IL-36 pathway demonstrates their potential as a therapeutic target for treating inflammatory skin diseases, such as generalized pustular psoriasis (GPP).A narrative review was written to further study preclinical and clinical evidence for the role of IL-36 in psoriasis ...
Jonwei Hwang +3 more
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