Results 41 to 50 of about 1,058,192 (273)
IL-36 cytokines in autoimmunity and inflammatory disease
The inteleukin-36 (IL-36) cytokines include IL-36α, IL-36β, IL-36γ and IL-36Ra, which belong to the IL-1 family and exert pro-inflammatory effects on various target cells such as keratinocytes, synoviocytes, dendritic cells and T cells. Emerging evidence has suggested a role of IL-36 in the pathogenesis of many inflammatory diseases. Here, we provide a
Ding, Liping +4 more
openaire +3 more sources
Consideration of serum IL‐36α and β levels trends in two patients with chikungunya fever
Key Clinical Message IL‐36 might play a role as an initial immune mechanism against chikungunya fever, and regulating IL‐36 production could be a potential treatment approach for this condition. Abstract Two Japanese siblings visited Cook Islands in 2015
Makoto Kondo +5 more
doaj +1 more source
Role of interleukin-36 in kidney disease
As an important member of IL-1 family, interleukin 36 (IL-36) is a key regulator of inflammation. Its proinflammatory agonists are composed of IL-36α, IL-36β and IL-36γ while its antagonists include IL-36Ra and IL-38.
Bi-xia Yang, Hua Zhou, Min Yang
doaj +1 more source
Review of the “Routledge Handbook of Philosophy of Sex and Sexuality”
This paper is a review essay of the recently published Routledge Handbook of Philosophy of Sex and Sexuality, edited by Brian D. Earp, Clare Chambers, and Lori Watson (2022). The anthology consists of an introduction and 40 essays, and it has eight parts:
Raja Halwani
doaj +1 more source
The Origin and Development of Prison Fellowship International: Pluralism, Ecumenism and American Leadership in the Evangelical World 1974–2006 [PDF]
Established in 1979 by Watergate felon Charles Colson, Prison Fellowship International (PFI) is now one of the largest para-church organizations in world evangelicalism.
Kendrick Oliver
core +2 more sources
IL-1 Family Cytokine Regulation of Vascular Permeability and Angiogenesis
The IL-1 family of cytokines are well-known for their primary role in initiating inflammatory responses both in response to and acting as danger signals.
Erin Fahey +4 more
doaj +1 more source
Psoriasis, a common inflammatory skin disease, is critically dependent on the IL-23/IL-17 cytokine axis. Although immune cell-derived IL-23 is generally associated with the disease pathogenesis, there have been reports of IL-23 production in ...
Young Joon Park +3 more
doaj +1 more source
Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis
Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these ...
Kazuhisa Furue +8 more
doaj +1 more source
Identification of novel molecular adjuvants which can boost and enhance vaccine-mediated immunity and provide dose-sparing potential against complex infectious diseases and for immunotherapy in cancer is likely to play a critical role in the next ...
Lumena Louis +5 more
doaj +1 more source
Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage [PDF]
Abstract IL-1 family members are central mediators of host defense. In this article, we show that the novel IL-1 family member IL-36γ was expressed during experimental colitis and human inflammatory bowel disease. Germ-free mice failed to induce IL-36γ in response to dextran sodium sulfate (DSS)-induced damage, suggesting that gut ...
Oscar Medina-Contreras +16 more
openaire +2 more sources

