Results 21 to 30 of about 6,730,703 (222)
Structural Basis of IL-1 Family Cytokine Signaling
Frontiers in Immunology, 2019 Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.
James K. Fields +6 more
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Sputum IL-25, IL-33 and TSLP, IL-23 and IL-36 in airway obstructive diseases. Reduced levels of IL-36 in eosinophilic phenotype. [PDF]
, 2021 peer reviewedINTRODUCTION: Alarmins ((IL-25, IL-33 and thymic stromal lymphopoietin (TSLP)) are known to promote Th2 inflammation and could be associated with eosinophilic airway infiltration.
Henket, Monique +7 more
core +1 more source
Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
International Journal of COPD, 2022 Nikolaos Pournaras,1,2 Anders Andersson,3,4 Melissa A Kovach,1 Médea Padra,5 Karlhans F Che,1,2 Bettina Brundin,1 Shigemi Yoshihara,6 Steven Bozinovski,7 Sara K Lindén,5 Per-Anders Jansson,8 Magnus C Sköld,2,9 Ingemar Qvarfordt,3,8 Anders Lindén1,2 ...
Pournaras N +12 more
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Frontiers in Immunology, 2022 Inflammation driven by environmental allergens is an important source of morbidity in diseases such as asthma and eczema. How common allergens promote inflammation is still poorly understood, but previous studies have implicated the protease activity ...
Valentina Frezza +4 more
doaj +1 more source
Clinical, Cosmetic and Investigational Dermatology, 2023 Jason E Hawkes,1,* Dale V Reisner,2 Tina Bhutani3,* 1Department of Dermatology, University of California at Davis, Sacramento, CA, USA; 2Patient Author, Yankton, SD, USA; 3Psoriasis and Skin Treatment Center, Department of Dermatology, University
Hawkes JE, Reisner DV, Bhutani T
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Cell Reports, 2020 Summary: Epithelial tissues represent vital interfaces between organisms and their environment. As they are constantly exposed to harmful pathogens, innocuous commensals, and environmental microbes, it is essential they sense and elicit appropriate ...
Thomas Macleod +11 more
doaj +1 more source
The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
Frontiers in Immunology, 2021 The skin barrier would not function without IL-1 family members, but their physiological role in the immunological aspects of skin barrier function are often overlooked.
Tom Macleod +8 more
doaj +1 more source
Frontiers in Immunology, 2023 Generalized pustular psoriasis (GPP) is a rare, chronic, inflammatory skin disorder characterized by recurrent flares associated with skin erythema, desquamation, and widespread superficial sterile pustules, which may be severe (“lakes of pus”). Systemic
Jason E. Hawkes +2 more
doaj +1 more source
IL‐36 cytokines and gut immunity
, 2021 Interleukin 36 (IL‐36) constitutes a group of cytokines that belong to the IL‐1 superfamily. Emerging evidence has suggested a role of IL‐36 in the pathogenesis of many inflammatory disorders.
Kuczma, Michal +7 more
core +1 more source
Consideration of serum IL‐36α and β levels trends in two patients with chikungunya fever
Clinical Case Reports, 2023 Key Clinical Message IL‐36 might play a role as an initial immune mechanism against chikungunya fever, and regulating IL‐36 production could be a potential treatment approach for this condition. Abstract Two Japanese siblings visited Cook Islands in 2015
Makoto Kondo +5 more
doaj +1 more source