Results 11 to 20 of about 6,730,703 (222)

IL-36-related genes predict prognosis of gastric cancer [PDF]

Frontiers in Oncology
IntroductionGastric cancer (GC) is one of the most frequently encountered malignant tumors in the clinic. Because effective early screening techniques are lacking, most patients have advanced disease at first diagnosis.
Ying Zhang, Yanbo Liu, Xin Guan, Meng Qu, Dianxiu Wu, Ning Liu, Zhengkun Lin, Yuqi Liu, Han Wang, Lijuan Yang   +9 more
doaj   +2 more sources

Influence of serum IL-36 subfamily cytokines on clinical manifestations of asthma [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: The IL-36 subfamily, a member of the IL-1 superfamily, is thought to promote type 2 (T2) and non-T2 inflammation and involved in autoimmune and airway disease progression. However, its role in asthma remains unclear.
Yuki Hoshino, MD, Tomoyuki Soma, MD, PhD, Kazuyuki Nakagome, MD, PhD, Reina Ishii, MD, Tatsuhiko Uno, MD, Kazuki Katayama, MD, Hidetoshi Iemura, MD, Erika Naitou, MD, Takahiro Uchida, MD, PhD, Yoshitaka Uchida, MD, PhD, Hidetoshi Nakamura, MD, PhD, Makoto Nagata, MD, PhD   +11 more
doaj   +2 more sources

Cathepsin G cleaves and activates IL-36γ and promotes the inflammation of psoriasis

Drug Design, Development and Therapy, 2019
Jing Guo,1,* Jie Tu,1,* YingYing Hu,1,2,* GuoXin Song,3 ZhiQiang Yin1 1Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China; 2Department of Medical Cosmetology, Wuqing People’s Hospital ...
Guo J, Tu J, Hu YY, Song GX, Yin ZQ
doaj   +1 more source

The new external drug for the treatment of psoriasis based on inhibition of serine proteases

Vestnik Dermatologii i Venerologii, 2021
Background: Psoriasis is a chronic inflammatory immune-mediated disease characterized by an increased rate of keratinocyte division. The results of recent studies have made it possible to establish that the cytokines of the IL-36 family occupy a ...
Alexander S. Zhukov, Evgeny R. Zharun, Vladislav R. Khairutdinov, Alexey V. Samtsov, Mihail Yu. Krasavin, A. V. Garabagiou   +5 more
doaj   +1 more source

Infiltrative-Suppurative Form of Scalp Microsporia in a Child with Generalized Pustular Psoriasis of von Zumbusch: Clinical Case

Вопросы современной педиатрии, 2021
Background. This article discusses issues of diagnosis and management of pustular psoriasis in a child associated with recurrent dermatomycosis, immunopathogenetic mechanisms of pustular psoriasis, its course and prognosis. Clinical Case Description. The
Andrey L. Bakulev, Sergey S. Kravchenya, Irina A. Igonina   +2 more
doaj   +1 more source

IkBζ is a Key Regulator of Tumour Necrosis Factor-a and Interleukin-17A-mediated Induction of Interleukin-36g in Human Keratinocytes

Acta Dermato-Venereologica, 2021
The interleukin (IL)-36 cytokine family plays an essential role in inflammatory processes in the skin and is implicated in the pathogenesis of psoriasis. This study explored the role of IL-36 in psoriasis and investigated the molecular mechanism involved
Sofie Kaas Ovesen, Klaus Schulze-Osthoff, Lars Iversen, Claus Johansen   +3 more
doaj   +1 more source

Effect of YangxueJiedu Decoction on the expression levels of IL-36 in psoriasis-like lesions in mice

Pifu-xingbing zhenliaoxue zazhi, 2021
Objective: To explore the effect of YangxueJiedu decoction on IL-36 expression in a mouse model of imiquimod-induced psoriasis-like lesions. Methods: Eighteen mice were randomly divided into the control, model and experimental groups, with 6 mice per ...
Qi ZHANG, Lei ZHU, Yuqi HUANG, Yongfeng CHEN   +3 more
doaj   +1 more source

IL-Info 36

, 1997
IL-INFO 36 IL-Info / Institut für Leichte Flächentragwerke (-) IL-Info 1-18 (1969 [6.-8-]) ( - ) IL-Info 1 (1.1970 eng) (-) IL-Info 2 (2. 1971 eng) (-) IL-Info 3 (3. 1971 eng) (-) IL-Info 4 (4. 1971 eng) (-) IL-Info 5
Universität Stuttgart. Institut für Leichte Flächentragwerke
core   +5 more sources

IL-36 receptor antagonist with special emphasis on IL-38.

, 2013
IL-36 is another family member of IL-1 and induces the production of proinflammatory cytokines and activates MAPK and NFkB pathways. IL-36 is a common mediator of innate and adaptive immune response and is inhibited by IL-36 receptor antagonist (RA).
Caraffa A, Shaik Y, Maccauro G, Murmura G, Galzio R, Potalivo G, Conti P, Antinolfi P, Theoharides TC, Maccauro, G, Pandolfi, Franco, Sabatino G, Pandolfi F, Conti F, Rosati M, Cianchetti E, Varvara G, Saggini A   +17 more
core   +3 more sources

Targeting IL-36 in Inflammatory Skin Diseases [PDF]

, 2023
Interleukin (IL)-36 cytokines are members of the IL-1 superfamily of cytokines. IL-36 cytokines are composed of three agonists (IL-36α, IL-36β, and IL-36γ) and two antagonists (IL-36 receptor antagonist [IL36Ra] and IL-38).
Ryo Fukaura, Masashi Akiyama, Akiyama, Masashi, Fukaura, Ryo   +3 more
core   +1 more source