Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression [PDF]
Lung cancer continues to be the leading cause of cancer-related deaths worldwide due to its high incidence, malignant behaviour and lack of major advancements in treatment strategy.
Feng Wang +3 more
doaj +1 more source
Aberrant Expression of Three New Members of IL-1 Family (IL-36α, IL-37 and IL-38) in Patients with Multiple Sclerosis [PDF]
Background & Objective: Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by demyelination and neuronal dysfunction. The study of the expression of cytokine genes seems to be an appropriate option for assessing their potential ...
Forouzan Ahmadi Khoei +2 more
doaj
IL-38 Aggravates Atopic Dermatitis via Facilitating Migration of Langerhans cells. [PDF]
Atopic dermatitis (AD) is a common inflammation skin disease that involves dysregulated interplay between immune cells and keratinocytes. Interleukin-38 (IL-38), a poorly characterized IL-1 family cytokine, its role and mechanism in the pathogenesis of AD is elusive.
Yue C +21 more
europepmc +3 more sources
IL-38 prevents induction of trained immunity by inhibition of mTOR signaling. [PDF]
Abstract Trained immunity is the acquisition of a hyperresponsive phenotype by innate immune cells (such as monocytes and macrophages) after an infection or vaccination, a de facto nonspecific memory dependent on epigenetic and metabolic reprogramming of these cells.
de Graaf DM +6 more
europepmc +6 more sources
Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a new member of anti-inflammatory cytokines.
Ning Yang +6 more
doaj +1 more source
Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome. [PDF]
The aim of this study was to investigate the expression of the interleukin (IL)-36 axis in patients with primary Sjögren's syndrome (pSS). Blood and minor labial salivary glands (MSG) biopsies were obtained from 35 pSS and 20 non-Sjögren's syndrome ...
Accardo Palumbo A +11 more
core +2 more sources
Thermo-statistical description of gas mixtures from space partitions [PDF]
The new mathematical framework based on the free energy of pure classical fluids presented in [R. D. Rohrmann, Physica A 347, 221 (2005)] is extended to multi-component systems to determine thermodynamic and structural properties of chemically complex ...
F. J. Rogers +12 more
core +3 more sources
Performance and Operational Transformation for Effective Water Network Management
In the management of drinking water networks, operational costs generally play second fiddle to capital investment costs, because their optimization strategies are often distinct. However, under the pressure of an aged network infrastructure with limited
Huan Yin +5 more
doaj +1 more source
IL-38: A new factor in rheumatoid arthritis
The newly characterized cytokine IL-38 (IL-1F10) belongs to the IL-1 family of cytokines. Previous work has demonstrated that IL-38 inhibited Candida albicans-induced IL-17 production from peripheral blood mononuclear cells. However, it is still unclear whether IL-38 is an inflammatory or an anti-inflammatory cytokine.
Takenaka, Shin-ichi +13 more
openaire +2 more sources
Serum interleukin 38 (IL-38) as a new potential biomarker of pediatric asthma
Background Bronchial asthma is considered the most prevalent chronic respiratory disease worldwide and is one of the main causes of hospitalization in the pediatric population.
Asmaa Kamal +3 more
doaj +1 more source

