Exploring the clinical significance of IL-38 correlation with PD-1, CTLA-4, and FOXP3 in colorectal cancer draining lymph nodes [PDF]
Frontiers in ImmunologyIntroductionColorectal cancer (CRC) presents a substantial challenge characterized by unacceptably high mortality and morbidity, primarily attributed to delayed diagnosis and reliance on palliative care.
Liuhong Yuan +6 more
doaj +2 more sources
Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression [PDF]
Open Biology, 2018 Lung cancer continues to be the leading cause of cancer-related deaths worldwide due to its high incidence, malignant behaviour and lack of major advancements in treatment strategy.
Feng Wang +3 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a new member of anti-inflammatory cytokines.
Ning Yang +6 more
doaj +1 more source
Aberrant Expression of Three New Members of IL-1 Family (IL-36α, IL-37 and IL-38) in Patients with Multiple Sclerosis [PDF]
Journal of Advanced Biomedical Sciences, 2023 Background & Objective: Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by demyelination and neuronal dysfunction. The study of the expression of cytokine genes seems to be an appropriate option for assessing their potential ...
Forouzan Ahmadi Khoei +2 more
doaj
Serum interleukin 38 (IL-38) as a new potential biomarker of pediatric asthma
The Egyptian Journal of Bronchology, 2022 Background Bronchial asthma is considered the most prevalent chronic respiratory disease worldwide and is one of the main causes of hospitalization in the pediatric population.
Asmaa Kamal +3 more
doaj +1 more source
Clinical implications of the novel cytokine IL-38 expressed in lung adenocarcinoma: Possible association with PD-L1 expression. [PDF]
PLoS ONE, 2017 Interleukin (IL)-38, a novel member of the IL-1 cytokine family, is homologous to IL-1 receptor antagonist (IL-1Ra) and IL-36Ra, and has been reported to act as an antagonist.
Kazuki Takada +12 more
doaj +1 more source
The role of IL-26 and IL-38 levels on menopause and vasomotor symptoms: a cross-sectional study
Ginekologia PolskaOBJECTIVES: Investigations into interleukins as predictors of vasomotor symptoms in the postmenopausal period have yielded mixed results. There is a growing interest in defining the complete cytokine profile during menopause.
Sultan Can +4 more
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Pifu-xingbing zhenliaoxue zazhi, 2023 Objective To investigate the roles of cytokines, IL-36γ and IL-38, in the inflammatory response in psoriasis vulgaris. Methods Both serum and peripheral blood mononuclear cells (PBMC) were collected from 29 patients with psoriasis vulgaris (PV) and 19 ...
Jiao ZHANG +4 more
doaj +1 more source
The severity of imiquimod-induced mouse skin inflammation is independent of endogenous IL-38 expression. [PDF]
PLoS ONE, 2018 The IL-1 cytokine family includes eleven members, among which Il-36α, β and γ, IL-36Ra and IL-38. The IL-36 cytokines are involved in the pathogenesis of psoriasis.
Jennifer Palomo +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source