Results 31 to 40 of about 984,354 (150)

IL-38: A novel cytokine in systemic lupus erythematosus pathogenesis. [PDF]

J Cell Mol Med, 2020
AbstractIL‐38 is a newly identified cytokine that belongs to the IL‐1 family. In our previous study, we found elevated plasma levels of IL‐38 in patients with systemic lupus erythematosus (SLE). However, the clear relationship of IL‐38 expression in plasma, peripheral blood mononuclear cells (PBMCs) and clinical and laboratory features needs ...
Xu WD, Su LC, Liu XY, Wang JM, Yuan ZC, Qin Z, Zhou XP, Huang AF.   +7 more
europepmc   +4 more sources

Aberrant Expression of Three New Members of IL-1 Family (IL-36α, IL-37 and IL-38) in Patients with Multiple Sclerosis [PDF]

Journal of Advanced Biomedical Sciences, 2023
Background & Objective: Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by demyelination and neuronal dysfunction. The study of the expression of cytokine genes seems to be an appropriate option for assessing their potential ...
Forouzan Ahmadi Khoei, Somayeh Reiisi, Parisa Mohammadinejad   +2 more
doaj  

IL-38 Aggravates Atopic Dermatitis via Facilitating Migration of Langerhans cells. [PDF]

Int J Biol Sci
Atopic dermatitis (AD) is a common inflammation skin disease that involves dysregulated interplay between immune cells and keratinocytes. Interleukin-38 (IL-38), a poorly characterized IL-1 family cytokine, its role and mechanism in the pathogenesis of AD is elusive.
Yue C, Hu Y, Yu J, Zhou H, Zhou P, Hu J, Wang X, Gu L, Li Y, Feng Y, Zeng F, Zhao F, Li G, Zhao Q, Zhang C, Zheng H, Wu W, Cui X, Huang N, Wang Z, Cui K, Li J.   +21 more
europepmc   +3 more sources

IL-38 prevents induction of trained immunity by inhibition of mTOR signaling. [PDF]

J Leukoc Biol, 2021
Abstract Trained immunity is the acquisition of a hyperresponsive phenotype by innate immune cells (such as monocytes and macrophages) after an infection or vaccination, a de facto nonspecific memory dependent on epigenetic and metabolic reprogramming of these cells.
de Graaf DM, Teufel LU, van de Veerdonk FL, Joosten LAB, Netea MG, Dinarello CA, Arts RJW.   +6 more
europepmc   +6 more sources

Elevated Interleukin-38 Level Associates with Clinical Response to Atorvastatin in Patients with Hyperlipidemia

Cellular Physiology and Biochemistry, 2018
Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a new member of anti-inflammatory cytokines.
Ning Yang, Yanqiu Song, Bo Dong, Yang Li, Lu Kou, Jingyu Yang, Qin Qin   +6 more
doaj   +1 more source

Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome. [PDF]

, 2015
The aim of this study was to investigate the expression of the interleukin (IL)-36 axis in patients with primary Sjögren's syndrome (pSS). Blood and minor labial salivary glands (MSG) biopsies were obtained from 35 pSS and 20 non-Sjögren's syndrome ...
Accardo Palumbo A, Alessandri C, ALESSANDRO, Riccardo, Carubbi F, CICCIA, Francesco, Giacomelli R, GUGGINO, Giuliana, Priori R, RAIMONDO, Stefania, Rizzo A, TRIOLO, Giovanni, Valesini G   +11 more
core   +2 more sources

Lyapunov spectra of periodic orbits for a many-particle system [PDF]

, 2001
The Lyapunov spectrum corresponding to a periodic orbit for a two dimensional many particle system with hard core interactions is discussed. Noting that the matrix to describe the tangent space dynamics has the block cyclic structure, the calculation of ...
Dettmann, Carl P., Morriss, Gary. P., Taniguchi, Tooru   +2 more
core   +2 more sources

IL-38: A new factor in rheumatoid arthritis

Biochemistry and Biophysics Reports, 2015
The newly characterized cytokine IL-38 (IL-1F10) belongs to the IL-1 family of cytokines. Previous work has demonstrated that IL-38 inhibited Candida albicans-induced IL-17 production from peripheral blood mononuclear cells. However, it is still unclear whether IL-38 is an inflammatory or an anti-inflammatory cytokine.
Takenaka, Shin-ichi, Kaieda, Shinjiro, Kawayama, Tomotaka, Matsuoka, Masanobu, Kaku, Yoichiro, Kinoshita, Takashi, Sakazaki, Yuki, Okamoto, Masaki, Tominaga, Masaki, Kanesaki, Katsuya, Chiba, Asako, Miyake, Sachiko, Ida, Hiroaki, Hoshino, Tomoaki   +13 more
openaire   +2 more sources

Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia. [PDF]

, 2019
Dasatinib, a second-generation BCR-ABL1 tyrosine kinase inhibitor, is approved for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia, both as first-line therapy and after imatinib intolerance or ...
Abruzzese, Elisabetta, Cortes, Jorge E, Hochhaus, Andreas, Hughes, Timothy P, Laneuville, Pierre, Lipton, Jeffrey H, Paar, David, Rea, Delphine, Rousselot, Philippe, Shah, Neil P, Snyder, David S   +10 more
core   +2 more sources

Serum interleukin 38 (IL-38) as a new potential biomarker of pediatric asthma

The Egyptian Journal of Bronchology, 2022
Background Bronchial asthma is considered the most prevalent chronic respiratory disease worldwide and is one of the main causes of hospitalization in the pediatric population.
Asmaa Kamal, Christine W. S. Basanti, Mahmoud A. Kaushty, Azza K. Abdelmegeid   +3 more
doaj   +1 more source