Results 91 to 100 of about 55,844,280 (246)

Association between interleukin-39 (IL-39) with hormonal and metabolic changes in women with polycystic ovarian syndrome

open access: yesAnaesthesia, Pain & Intensive Care
Background & Objective: The most prevalent endocrine defect affecting women in their reproductive years is called polycystic ovarian syndrome (PCOS). It is strongly correlated to metabolic syndrome, insulin resistance, and an increased risk of diabetes and cardiovascular disease in the future.
Hanaa Addai Ali, Kawther Mejbel Hussein
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Il Dio della politica

open access: yes, 2007
Il complesso rapporto tra politica e religione nella Repubblica Islamica. Khomeini e la rottura con la tradizione religiosa sciita.
GUOLO, RENZO
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Association of peripheral inflammatory cytokines with motor and non-motor symptoms in patients with Parkinson’s disease and type 2 diabetes mellitus

open access: yesFrontiers in Neurology
ObjectiveThis pilot study aims to investigate the association between peripheral inflammatory cytokines and motor and non-motor symptoms in patients with both Parkinson’s disease (PD) and type 2 diabetes mellitus (T2DM) and the underlying mechanisms ...
Aiping Hu   +9 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Imaux.

open access: yesEspacesTemps.net, 2002
Le roman d'Étienne Villain présente un personnage qui accomplit durant l'automne 1998 une cure de désintoxication orchestrée par l'association Un Automne Sans Alcool, dite aussi uasa . Cet homme se livre.
Estelle Rauzy
doaj  

IL-10: the master regulator of immunity to infection.

open access: yes, 2008
IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK cells, and macrophages, all of which are required for optimal pathogen clearance but also contribute to tissue damage.
Couper, Kevin N   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Le Sénat, du territoire aux citoyens.

open access: yesEspacesTemps.net, 2004
Au terme des élections régionales et cantonales de mars 2004, il apparaît que le débat fut surtout national et que le traitement médiatique, mais aussi politique qui en est fait ne présente pas de distinction claire entre l'enjeu politique dont il ...
Boris Beaude
doaj  

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