Results 141 to 150 of about 55,844,280 (246)

The Interleukin-12 Family Serum Levels (IL-12, IL-23, IL-27, IL-35, and IL-39) in Iraqi Females Breast Cancer Patients: A Case-Control Study

Abstract Breast cancer is the commonest cancer among women in Iraq and has a significant public health impact. Interleukin-12 family cytokines, along with interleukin-23 (IL-23), interleukin-27 (IL-27), and, more recently identified as a member of the family, interleukin 39 (IL-39) and interleukin 35 (IL-35), are essential for immune ...
Osama Al-Saffar, Ahmed Al-Dabbagh
openaire   +1 more source

Role of IL-1 Family Cytokines IL-36, IL-37, IL-38 in Osteoarthritis and Rheumatoid Arthritis: A Comprehensive Review [PDF]

Yuan Xu, Jing-Yan Wang, Yang Zou, Xue-Wei Ma, Tian Meng College of Health Industry, Sichuan Tourism University, Chengdu, Sichuan, 610100, People’s Republic of ChinaCorrespondence: Yuan Xu, Email 230973159@qq.comAbstract: Inflammatory cytokines ...
Zou Y, Ma XW, Meng T, Wang JY, Xu Y
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

La carte des primaires, mode d'emploi.

EspacesTemps.net, 2004
L'irruption dans la presse de ce qu'il est convenu d'appeler le « multimédia » pose deux questions à qui s'intéresse aux cartes en général, et à celles publiées dans la presse en particulier.
Patrick Poncet
doaj  

Il Popolo dei non nati

, 2011
Il contributo analizza il rapporto tra i recenti cambiamenti demografici che l'Italia sta attraversando e la legge 194/1978 sull'interruzione volontaria di gravidanza, mettendo in luce l'incidenza dell'aborto sul calo demografico e soprattutto sull ...
Gambino, G, GAMBINO, GABRIELLA
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Une science impériale pour l'Afrique ?

EspacesTemps.net, 2004
C'est un livre passionnant qui, dans sa forme de thèse, peut apparaître quelque peu ardu pour un lecteur non familier des productions de l' Ehess .
Jean-Yves Barrère
doaj  

Faculty Opinions recommendation of Lack of evidence for expression and function of IL-39 in human immune cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2021
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source