Results 121 to 130 of about 55,844,280 (246)

L’échangeur au dragon.

EspacesTemps.net, 2005
Shanghai, 24 août 2005, sous le pilier dort un dragon. Sous quatre niveaux de doubles ou triples voies enchevêtrées, et de quelques passages pour les rares piétons qui oseraient traverser, il dort. Quel chaos s'il se réveillait.
Clarisse Didelon
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

, 2007
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130.
A Murray, Henley, W, Bandinelli, S, S Rafiq, Rafiq, S, Weedon, MN, Guralnik, JM, Hurst, A, A-M Corsi, Ferrucci, L, K Stevens, S Bandinelli, M N Weedon, Corsi, A-M, L Ferrucci, Murray, A, D Melzer, W Henley, T M Frayling, J M Guralnik, A Hurst, Stevens, K, Melzer, D, Frayling, TM   +23 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Investigating Role of IL-39, IL-37 and Some Biochemical Parameters in Patients with Acute Interstitial Nephritis

Indonesian Journal on Health Science and Medicine
Background: Acute interstitial nephritis causes blood flow to be impaired, this ultimately leads to inflammation and edema in the renal tubules and tissues, this decreases the glomerular filtration rate (GFR). Early detection and treatment of the disease can mitigate the progression of renal failure.
openaire   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Progetto CR-39 Quality di EURADOS per il miglioramento e l’armonizzazione della dosimetria neutronica personale con CR-39

, 2021
I rivelatori a tracce CR-39 sono tra gli strumenti più diffusi nell’ambito della dosimetria neutronica poiché permettono di realizzare semplici ed economici dosimetri passivi adatti alle applicazioni radioprotezionistiche in una vasta gamma di ...
M. Bolzonella, M. Caresana
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Alterations in IL-32, IL-39, and LDH Serum Levels in Iraqi Patients with Acute Leukemia: A Cross-Sectional Comparison of Newly diagnosed and Previously Treated Cohorts

Asian Pacific Journal of Cancer Care
Introduction: Acute leukemia (AL), are marked by abnormal differentiation and uncontrolled proliferation of cancerous hematopoietic stem cells. These malignant cells build up in the bone marrow, inhibiting the development and maturation of healthy blood cells.
Noor S. Al-Zubaidi, Rasha M. Alhumairi
openaire   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source