Results 131 to 140 of about 55,844,280 (246)

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Il settore Lattanzi della necropoli di Norchia ed il contesto della tomba 3

open access: yes
Il capitolo presenta il contesto e lo scavo della tomba della necropoli dei Lattanzi a Norchia, in cui nel 2024 è stato rinvenuto uno stamnos decorato e ...
Daniel Morleghem
core  

Evaluation of salivary asprosin, IL-39, IL-40, and IL-1β levels in diabetic patients with periodontitis [PDF]

open access: yes
Giriş: Periodontal hastalıklar, mikrobiyal dental plaklara karşı gelişen konak yanıtının neden olduğu kronik inflamatuar hastalıklardır. Diabetes mellitus gibi sistemik hastalıklar, periodontal dokulardaki inflamasyonu şiddetlendirebilir.
Oruç, Ayşe Hümeyra
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

La morte e il diritto: il problema dei trapianti d’organo (Profilo penalistico)

open access: yes, 1994
L’intervento è circoscritto ai casi di espianto d’organi dai defunti, con esclusione delle ipotesi di trapianti tra viventi. Dal punto di vista penalistico si esclude la tutelabilità del cadavere in quanto tale, che viene considerato solo come oggetto ...
ALESSANDRI, ALBERTO
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Adult-onset Still's disease: current challenges and future prospects

open access: yesOpen Access Rheumatology: Research and Reviews, 2016
Mariam Siddiqui,1 Michael S Putman,2 Anisha B Dua,11Department of Rheumatology, 2Department of Internal Medicine, The University of Chicago Medical Center, Chicago, IL, USA Abstract: Adult-onset Still's disease (AOSD) – a multi-systemic ...
Siddiqui M, Putman MS, Dua AB
doaj  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Colloque : «  Apprendre l'histoire et la géographie à l'École  ».

open access: yesEspacesTemps.net, 2003
Un Colloque sur l'enseignement de l'histoire-géographie à l'école s'est tenu à Paris les 12, 13 et 14 décembre 2002 à l'initiative de l'inspection générale et de la Direction de l'enseignement scolaire.
Christian Grataloup, François Dosse
doaj  

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