Results 161 to 170 of about 14,944,976 (275)

Profile of mRNA Expression of IL-6 and IL-10 in Breast Cancer Patients with or Without Chemotherapy

, 2015
-Background. Breast can er 's "1 yp of cancer t t has high pfeval nee, car occt in in 1 n v oniefi\ud ones are factors that are known to have good properties of tumor growth and tumor inhibitory effects Cytokine has an\ud #tho .- iv fn' ,L uc, att e ai-
Asadul Islam, Andi
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Context-dependent regulation of IL-6 in exercise and colorectal cancer cachexia. [PDF]

Front Oncol
Xiong J, Liu S, Xu J, Zhang J, Peng Y, Xia Y, Qian J.   +6 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

IL-6 trans-signaling in cancer metabolism, multidrug resistance, and chronic inflammation. [PDF]

J Biol Chem
Melisi F, Pasquale LS, Peluso T, Graziano C, Iannarone C, Vicario M, De Iesu MR, Izzo M, Ricciardi R, Bocchetti M, Cossu AM, Matarese G, Scrima M, Caraglia M.   +13 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

IL-6 Promotes Pathological Angiogenesis in Oral Submucous Fibrosis by Suppressing USP10-VEGFR1 Interaction. [PDF]

J Cell Mol Med
Li C, Han L, Wang Z, Xie Y, Xu X, Chen Q, Xie L.   +6 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Choroidal thickness as a biomarker of inflammatory activity in patients with polymyalgia rheumatica receiving anti-IL-6 treatment. [PDF]

Front Med (Lausanne)
Trives-Folguera L, Muñoz-Fernández S, Del Mar Esteban-Ortega M, Leyva-Esteban J, Coca-Serrano R, Cobo-Ibañez T, Vergara-Dangond C, Romero-Bogado L, de la Cámara-Fernández I, Richi P, Paredes MB, Esteban-Vazquez A, Acosta AV, Cueva-Najera G, Algarra-San José M, Thuissard-Vasallo I, Steiner M.   +16 more
europepmc   +1 more source

Characterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP [PDF]

Journal of Biological Chemistry, 2007
Silke Metz, Monique Wiesinger, Michael Vogt, Heike Lauks, Günther Schmalzing, Peter C. Heinrich, Gerhard Müller-Newen   +6 more
openaire   +1 more source