Results 201 to 210 of about 2,244,987 (335)

ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma

, 2017
Mi Ran Yun, Hyantae Choi, Hari Kang, YW Lee, H Joo, D H Kim, Hye Ryun Kim, Min Hee Hong, Sun Och Yoon, Byoung Chul Cho   +9 more
openalex   +2 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

HLA-G, IL-6 and TGF-β in Seminal Plasma as Potential Biomarkers of ART Outcome. [PDF]

Am J Reprod Immunol
Schallmoser A, Emrich N, Masslow L, Allam JP, Einenkel R, Sänger N.   +5 more
europepmc   +1 more source

IL-6; IL-6 receptor (IL-6R; CD126); IL-6 signal transducer (IL-6ST; gp130; CD130) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Characterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP [PDF]

Journal of Biological Chemistry, 2007
Silke Metz, Monique Wiesinger, Michael Vogt, Heike Lauks, Günther Schmalzing, Peter C. Heinrich, Gerhard Müller-Newen   +6 more
openaire   +1 more source

The association of IL-1β, IL-1α, IL-6, and E-selectin with the diastolic dysfunction in patients with type 2 diabetes mellitus and preserved ejection fraction

Dejan Marinkovic, Tamara Dragovic, Predrag Djurić, Jelena Rakočević, Dragana Malovic, Sasa Kikovic, Ivan Stanojević, Bratislav Dejanović, Petar Ristić, Zoran Hajdukovic   +9 more
openalex   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Progesterone and IL-6 Expression Are Modulated by Follicular Fluid in Granulosa Cell Cultures. [PDF]

Biomolecules
Marin L, Sabbadin C, Radu CM, Brun P, Frison C, Gullo G, Armanini D, Bordin L, Ragazzi E, Ambrosini G, Andrisani A.   +10 more
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Pro-Inflammatory Signaling in Dermal Fibroblasts: A Possible Role of Different Botulinum Toxin Formulations on IL-6 Expression. [PDF]

J Cosmet Dermatol
Sommatis S, Mocchi R, Di Francesco S, Bighetti S, Bettolini L, Carugno A, Paolino G, Rossi M, Guida S, Valenti M, Zerbinati N.   +10 more
europepmc   +1 more source