Results 201 to 210 of about 1,851,762 (241)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Ellagic acid is associated with reduced pancreatic carcinogenesis and modulation of the IL-6/STAT3 pathway. [PDF]

open access: yesGenes Environ
Kato H   +7 more
europepmc   +1 more source

Synergistic HA-tooth graft composite promotes rapid alveolar bone healing via IL-6 suppression and OCN enhancement. [PDF]

open access: yesJ Oral Biol Craniofac Res
Indrawati DW   +6 more
europepmc   +1 more source

The effect of oral protein and carbohydrate solution administration on NLR, IL-6 and CRP levels in patients undergoing surgery. [PDF]

open access: yesJ Crit Care Med (Targu Mures)
Adhi MP   +5 more
europepmc   +1 more source

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