Results 291 to 300 of about 2,244,987 (335)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Dioscin attenuates Gd-IgA1 overproduction by inhibiting the IL-6-JAK2/STAT3 signaling axis in IgA nephropathy. [PDF]

BMC Nephrol
Lin L, Li H, Zhou S, Zheng L, Sun S, Li S.   +5 more
europepmc   +1 more source

NFκB/IL-6/JAK2/STAT axis in myelofibrosis is a key vulnerability that is targetable and relevant to JAK2 inhibitor treatment resistance. [PDF]

Blood Cancer J
Bian H, Gangat N, Shen N, Pang J, Wald D, Tse W, Tefferi A, Yan F, Liu S.   +8 more
europepmc   +1 more source

Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, TNF-α and IL-6, but accentuates degradation above a strain threshold

, 2013
Yang Li, Eliot H. Frank, Yang Wang, Susan Chubinskaya, Han-Hwa Huang, Alan J. Grodzinsky   +5 more
openalex   +1 more source

Innate immune role of IL-6 in influenza a virus pathogenesis. [PDF]

Front Cell Infect Microbiol
Li X, Huang C, Rai KR, Xu Q.
europepmc   +1 more source

Dual-pathway model of IL-6 and HSP22/HSP27 dynamics predicts post-PCI MACE in STEMI patients. [PDF]

BMC Cardiovasc Disord
Hu Y, Liu Y, Wang Y, Lin F, Chen R, Chen C, Qu T.   +6 more
europepmc   +1 more source

Clinical application of butylphthalide sequential therapy on PTX-3, S100B, IL-6 in acute cerebral infarction. [PDF]

J Med Biochem
Meng P, Zhang J, Li J, Ji N, Zhou X, Xu B.   +5 more
europepmc   +1 more source

Expression of concern: "Recipient IL-6-572C/G genotype is associated with reduced incidence of acute rejection following liver transplantation". [PDF]

J Int Med Res
europepmc   +1 more source

Der Einfluss von IL-6 auf das Pankreas- und Kolorektalkarzinom

, 2015
Holmer, Reinhild
openalex   +1 more source