Results 261 to 270 of about 80,028,732 (285)
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Gan to kagaku ryoho. Cancer & chemotherapy, 1994
IL-7, a 25-kDa glycoprotein was cloned as a cytokine derived from bone marrow stromal cells, which induces proliferation of pre-B cells. IL-7 was found to be produced by the thymus, spleen, kidney and bone marrow stromal cells and induces proliferation of immature B and T cells.
M, Yasunaga, S, Nishikawa
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IL-7, a 25-kDa glycoprotein was cloned as a cytokine derived from bone marrow stromal cells, which induces proliferation of pre-B cells. IL-7 was found to be produced by the thymus, spleen, kidney and bone marrow stromal cells and induces proliferation of immature B and T cells.
M, Yasunaga, S, Nishikawa
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Science-Business eXchange, 2008
Canadian researchers have shown that IL-7 initiates disease in an animal model of type 2 diabetes and potentially other autoimmune conditions, but targeting the cytokine and its receptor will prove tricky.
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Canadian researchers have shown that IL-7 initiates disease in an animal model of type 2 diabetes and potentially other autoimmune conditions, but targeting the cytokine and its receptor will prove tricky.
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Cytokine, 1998
B lymphocyte development in mouse bone marrow (BM) occurs in association with stromal cells which provide essential growth factors, notably interleukin 7 (IL-7). The ability of recombinant IL-7 given systemically by several modes of administration to stimulate proliferation of precursor B cells at successive stages of development was examined.
H O, Valenzona +3 more
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B lymphocyte development in mouse bone marrow (BM) occurs in association with stromal cells which provide essential growth factors, notably interleukin 7 (IL-7). The ability of recombinant IL-7 given systemically by several modes of administration to stimulate proliferation of precursor B cells at successive stages of development was examined.
H O, Valenzona +3 more
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International Immunology, 1995
We have generated a high copy number transgenic mouse line in which expression of mouse IL-7 cDNA is under the control of the mouse MHC class II E alpha promoter. These mice were generated in order to see if IL-7 over-production in the thymus altered either thymocyte differentiation or the process of negative selection.
Mertsching, Elisabeth +2 more
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We have generated a high copy number transgenic mouse line in which expression of mouse IL-7 cDNA is under the control of the mouse MHC class II E alpha promoter. These mice were generated in order to see if IL-7 over-production in the thymus altered either thymocyte differentiation or the process of negative selection.
Mertsching, Elisabeth +2 more
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Bioconjugate Chemistry, 1998
Interleukin 7 (IL-7) induces the proliferation of B cell progenitors in long-term bone marrow cultures, promotes the growth of resting fetal and adult thymocytes, and costimulates mature human T cell proliferation. IL-7 also induces cell growth in hematologic malignancies such as acute lymphoblastic leukemia, chronic lymphocytic leukemia, acute ...
E B, Sweeney +3 more
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Interleukin 7 (IL-7) induces the proliferation of B cell progenitors in long-term bone marrow cultures, promotes the growth of resting fetal and adult thymocytes, and costimulates mature human T cell proliferation. IL-7 also induces cell growth in hematologic malignancies such as acute lymphoblastic leukemia, chronic lymphocytic leukemia, acute ...
E B, Sweeney +3 more
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Trends in Immunology, 2001
A recent report by researchers at the Gladstone Institute of Virology and Immunology in San Francisco shows that during HIV infection, interleukin 7 (IL-7) is responsible for T-cell production in response to T-cell depletion but that it also increases HIV-1 replication. In a study of 187 HIV-1 seropositive adults, levels of IL-7 were found to correlate
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A recent report by researchers at the Gladstone Institute of Virology and Immunology in San Francisco shows that during HIV infection, interleukin 7 (IL-7) is responsible for T-cell production in response to T-cell depletion but that it also increases HIV-1 replication. In a study of 187 HIV-1 seropositive adults, levels of IL-7 were found to correlate
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[Molecular aspects of IL-7-IL-7 receptor system].
Nihon rinsho. Japanese journal of clinical medicine, 1992IL-7 is a multifunctional cytokine which acts on cells such as B cells, T cells and macrophages. As the IL-7 clearly plays many important roles the in control of growth and differentiation, it is important to understand how IL-7 and IL-7 receptor (IL-7R) are expressed.
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Blood, 2006
Kim and colleagues demonstrate that aging is associated with diminished numbers of IL-7Rα–expressing T cells and that these cells have decreased responsiveness to IL-7, with important implications for the clinical development of IL-7 as an immunomodulatory agent.
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Kim and colleagues demonstrate that aging is associated with diminished numbers of IL-7Rα–expressing T cells and that these cells have decreased responsiveness to IL-7, with important implications for the clinical development of IL-7 as an immunomodulatory agent.
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1995
Abstract The nucleotide sequence of murine IL-7 was derived from a cDNA isolated from a bone marrow stromal cell line and predicted a protein composed of 129 amino acids (Namen et al. 1988) (GenBank accession number X07962). The human cDNA was isolated by cross-hybridization from a human hepatoma cell line (Goodwin et al. 1989).
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Abstract The nucleotide sequence of murine IL-7 was derived from a cDNA isolated from a bone marrow stromal cell line and predicted a protein composed of 129 amino acids (Namen et al. 1988) (GenBank accession number X07962). The human cDNA was isolated by cross-hybridization from a human hepatoma cell line (Goodwin et al. 1989).
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SYNTHETIC IL-7 AND IL-7 IMMUNOCYTOKINES
2023PATTABIRAMAN VIJAYA RAGHAVAN +5 more
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