BMC Immunology, 2010 Background Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens.
Pandey Akhilesh, Zhong Jun
doaj +1 more source
Characterization of the function of thymic stromal lymphopoietin in lymphopoiesis and lymph node organogenesis [PDF]
, 2010 Interleukin (IL)-7 is a cytokine, which is crucial for the development of the murine immune system. It is required for lymphopoiesis and for the development of peripheral lymph nodes (LN). IL-7-/-mice have impaired B and T cell lymphopoiesis, decreased
Chappaz, Stéphane
core +1 more source
The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core +1 more source
JunD/AP-1-mediated gene expression promotes lymphocyte growth dependent on interleukin-7 signal transduction. [PDF]
PLoS ONE, 2012 Interleukin-7 (IL-7) is an essential cytokine for lymphocyte growth that has the potential for promoting immune reconstitution. This feature makes IL-7 an ideal candidate for therapeutic development.
Shannon M Ruppert +5 more
doaj +1 more source
Treatment with IL5-/IL-5 receptor antagonists in drug reaction with eosinophilia and systemic symptoms (DRESS) [PDF]
, 2022 PURPOSE: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe delayed drug hypersensitivity reaction with exanthema, eosinophilia, and organ manifestations.
Simon Bossart +15 more
core +2 more sources
Frontiers in Immunology, 2019 Incorporation of inverted cytokine receptor (ICR) such as interleukin (IL)-4 vs. IL-7 (4/7) ICR is one strategy to improve the antitumor activities of chimeric antigen receptor (CAR) modified T (CAR-T) cells facing immunosuppressive cytokines.
Yi Wang +7 more
doaj +1 more source
Attenuation of IL-7 Receptor Signaling Is Not Required for Allelic Exclusion [PDF]
The Journal of Immunology, 2006 Abstract Allelic exclusion prevents pre-B cells from generating more than one functional H chain, thereby ensuring the formation of a unique pre-BCR. The signaling processes underlying allelic exclusion are not clearly understood. IL-7R-dependent signals have been clearly shown to regulate the accessibility of the Ig H chain locus ...
Wynette M, Will +7 more
openaire +2 more sources
Interleukin 7 from maternal milk crosses the intestinal barrier and modulates T-cell development in offspring [PDF]
, 2011 Background Breastfeeding protects against illnesses and death in hazardous environments, an effect partly mediated by improved immune function. One hypothesis suggests that factors within milk supplement the inadequate immune response of the offspring,
Andrew M Prentice +11 more
core +2 more sources
Mouse monocytes express CD127 by immune cells, not LPS
Frontiers in ImmunologyThe essential role of interleukin 7 (IL-7) signaling via its receptor (IL-7Rα; CD127) in T cell development and function has been well documented. However, CD127 expression and function in myeloid cells, including monocytes, are less clear, especially in
Reza Yazdani +7 more
doaj +1 more source
Effects of long non-coding RNA Gm14461 on pain transmission in trigeminal neuralgia
Journal of Inflammation, 2020 Background This study aims to investigate the role of long non-coding RNA Gm14461 in regulating pain transmission in trigeminal neuralgia (TN). The mouse TN model was produced by chronic constriction injury of the infraorbital nerve (CCI-ION). The values
Mu Xu +5 more
doaj +1 more source