Results 81 to 90 of about 18,317 (191)

Sleep Deprivation, Cytokine Dysregulation, and the Risk of Cardiac Arrhythmia in Dogs

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Sleep deprivation triggers systemic inflammation in dogs, activating cytokine networks (IL‐6, TNF, IFN‐γ) and JAK–STAT signalling. Network and enrichment analyses reveal immune‐cardiac interactions linked to altered electrophysiology and arrhythmia risk.
Adithya Sethumadhavan, Arun HS Kumar
wiley   +1 more source

Produção de citocinas IL-1,IL6 e CXCL8 por explantes endometriais de novilhas azebuadas estimuladas por diferentes padrões moleculares associados a patógenos [PDF]

open access: yes, 2017
The objective of this study was to evaluate the production of proinflammatory cytokines interleukin 1 (IL1), interleukin 6 (IL6) and chemokine CXCL8, by endometrial explants of zebu based heifers at diestrous stimulated by pathogen-associated molecular ...
Philipe Pimenta Nunes
core  

THE CYTOPROTECTIVE EFFECT OF INTERLEUKIN 4 ON FIBROBLASTS COCULTERED WITH THE MONONUCLEARS OF PATIENTS WITH TYPE 2 DIABETES MELLITUS AND THOSE WITH TYPE 2 DIABETES MELLITUS AND CHRONIC FOOT ULCERS IN A 3D CULTURE MODELhttp://dx.doi.org/10.25298/2221-8785-2020-18-4-410-416

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020
Our research focused on the role of immune mechanisms in diabetic foot ulcers development and impaired healing. A 3D skin culture system, as a relevant skin model, has proved valuable in investigating these mechanisms and is a useful tool to study ...
Mashkova M. A.   +2 more
doaj   +1 more source

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5389-5406, September 2026.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi   +10 more
wiley   +1 more source

Expediency of the study of the ESR1 [rs 2234693], CYP19A1 [rs2414096], and IL10 [rs1800896] single nucleotide polymorphisms as feasible markers of risk that malocclusion develops in persons born macrosomic

open access: yesPatologìâ, 2020
The article deals with analyzing the influence of polymorphic variants of CYP19A1 [rs2414096, rs936306], ESR1 [rs2234693, rs9340799], RANKL [rs9594738, rs9594759], IL1 [rs1143627], IL6 [rs1800796] and IL10 [rs1800896] genes on malocclusion development in
O. V. Garmash, Ye. M. Riabokon
doaj   +1 more source

Salivary concentration of TNFalpha, IL1 alpha, IL6, and IL8 in oral squamous cell carcinoma.

open access: yesMedicina oral, patologia oral y cirugia bucal, 2008
The aim of this study was to compare the concentration of tumor necrosis factor alpha, interleukin 1 alpha, 6, and 8 in the saliva of oral squamous cell carcinoma patients with control group.In this study 18 subjects were involved, nine patients with oral squamous cell carcinomas and nine age-sex-matched healthy individuals that were matched for ...
Mahnaz, SahebJamee   +3 more
openaire   +1 more source

Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses

open access: yesExploration, Volume 6, Issue 4, August 2026.
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li   +14 more
wiley   +1 more source

Hippo Pathway Regulation and Microenvironmental Cues Governing Human MSC Transition to Cancer‐Associated Fibroblasts

open access: yesJournal of Cellular Physiology, Volume 241, Issue 8, August 2026.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are key drivers of tumor progression. This study examined how three‐dimensional (3D) culture, hypoxia, and cancer‐derived soluble factors influence the transformation of human mesenchymal stem cells (hMSCs) into inflammatory CAFs (iCAFs). hMSCs from bone marrow, placenta, and chorion were cultured in 2D, in
Pimjai Chingsuwanrote   +7 more
wiley   +1 more source

INTERGENIC INTERACTIONS OF CYTOKINE GENES IL1, IL1RA, IL6, IL10 AND TNFА IN PATIENTS WITH IRRITABLE BOWEL SYNDROME AND ULCERATIVE COLITIS IN RUSSIAN POPULATION OF THE CHELYABINSK REGION

open access: yesMedical Immunology (Russia), 2018
Сomplex intergenic interactions should be taken into account when predicting the risk of adverse course in a pathological process. This presumption is at the heart of evolving multifactorial diseases (ulcerative colitis and irritable bowel syndrome). A single genetic polymorphism seems to be a weak risk factor when predicting the disease evolution and ...
D. S. Stashkevich   +3 more
openaire   +3 more sources

Changes in TNF-α, IL-10, Il-1β, IL-6, IFN-γ, CRP and GC in CSF at 121 days in sham and Nx (Nx-M and Nx-CI) groups.

open access: yes, 2015
Values are the mean ± S.E.M.
Tania Araujo Viel (736919)   +13 more
core   +1 more source

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