Results 81 to 90 of about 18,317 (191)
Sleep Deprivation, Cytokine Dysregulation, and the Risk of Cardiac Arrhythmia in Dogs
Sleep deprivation triggers systemic inflammation in dogs, activating cytokine networks (IL‐6, TNF, IFN‐γ) and JAK–STAT signalling. Network and enrichment analyses reveal immune‐cardiac interactions linked to altered electrophysiology and arrhythmia risk.
Adithya Sethumadhavan, Arun HS Kumar
wiley +1 more source
Produção de citocinas IL-1,IL6 e CXCL8 por explantes endometriais de novilhas azebuadas estimuladas por diferentes padrões moleculares associados a patógenos [PDF]
The objective of this study was to evaluate the production of proinflammatory cytokines interleukin 1 (IL1), interleukin 6 (IL6) and chemokine CXCL8, by endometrial explants of zebu based heifers at diestrous stimulated by pathogen-associated molecular ...
Philipe Pimenta Nunes
core
Our research focused on the role of immune mechanisms in diabetic foot ulcers development and impaired healing. A 3D skin culture system, as a relevant skin model, has proved valuable in investigating these mechanisms and is a useful tool to study ...
Mashkova M. A. +2 more
doaj +1 more source
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi +10 more
wiley +1 more source
The article deals with analyzing the influence of polymorphic variants of CYP19A1 [rs2414096, rs936306], ESR1 [rs2234693, rs9340799], RANKL [rs9594738, rs9594759], IL1 [rs1143627], IL6 [rs1800796] and IL10 [rs1800896] genes on malocclusion development in
O. V. Garmash, Ye. M. Riabokon
doaj +1 more source
Salivary concentration of TNFalpha, IL1 alpha, IL6, and IL8 in oral squamous cell carcinoma.
The aim of this study was to compare the concentration of tumor necrosis factor alpha, interleukin 1 alpha, 6, and 8 in the saliva of oral squamous cell carcinoma patients with control group.In this study 18 subjects were involved, nine patients with oral squamous cell carcinomas and nine age-sex-matched healthy individuals that were matched for ...
Mahnaz, SahebJamee +3 more
openaire +1 more source
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li +14 more
wiley +1 more source
ABSTRACT Cancer‐associated fibroblasts (CAFs) are key drivers of tumor progression. This study examined how three‐dimensional (3D) culture, hypoxia, and cancer‐derived soluble factors influence the transformation of human mesenchymal stem cells (hMSCs) into inflammatory CAFs (iCAFs). hMSCs from bone marrow, placenta, and chorion were cultured in 2D, in
Pimjai Chingsuwanrote +7 more
wiley +1 more source
Сomplex intergenic interactions should be taken into account when predicting the risk of adverse course in a pathological process. This presumption is at the heart of evolving multifactorial diseases (ulcerative colitis and irritable bowel syndrome). A single genetic polymorphism seems to be a weak risk factor when predicting the disease evolution and ...
D. S. Stashkevich +3 more
openaire +3 more sources

