Results 71 to 80 of about 18,317 (191)

Therapeutic Potential of Propolis in Ulcerative Colitis: A Review of Preclinical Evidence

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review compiles preclinical evidence from studies that investigate the therapeutic potential of propolis extracts derived from different botanical origins, as well as their main bioactive constituents, in the context of ulcerative colitis. The observed beneficial effects are primarily attributed to their antioxidant, immunomodulatory, and anti ...
Thayná Fernandes Barros, Gabriel Gomes Vila Nova, Rosane Nassar Meireles Guerra, Flavia Raquel Fernandes do Nascimento, Afonso Gomes Abreu   +4 more
wiley   +1 more source

Hydrocalumite‐Like Material Induces Early Osteogenic Priming and ECM Remodeling Without Effective Mineralization in Preosteoblasts

Journal of Biomedical Materials Research Part A, Volume 114, Issue 11, November 2026.
ABSTRACT Hydrocalumite‐like phases, belonging to the layered double hydroxide family, are potential biomaterials for bone repair; however, their cellular effects remain incompletely understood. Here, we evaluated a hydrocalumite‐like material of composition [Ca2Al(OH)₆]Cl·nH2O (abbreviated Ca2Al–Cl) in preosteoblastic MC3T3‐E1 cells, assessing ...
C. J. da Costa Fernandes, G. S. de Almeida, M. Pires Figueiredo, V. R. L. Constantino, W. F. Zambuzzi   +4 more
wiley   +1 more source

Biomarkers of fatigue related to adjuvant chemotherapy for breast cancer: evaluation of plasma and lymphocyte expression

Clinical and Translational Medicine, 2015
BackgroundFatigue is common in cancer patients receiving adjuvant chemotherapy. To further understand the mechanism of fatigue and search for potential biomarkers, we conducted this prospective study.
Felipe M Cruz, Bruna A Munhoz, Beatriz CA Alves, Flavia S Gehrke, Fernando LA Fonseca, Renata K Kuniyoshi, Daniel Cubero, Luke J Peppone, Auro delGiglio   +8 more
doaj   +1 more source

The Acute Phase Reaction and Its Prognostic Impact in Patients with Head and Neck Squamous Cell Carcinoma: Single Biomarkers Including C-Reactive Protein Versus Biomarker Profiles

Biomedicines, 2020
C-reactive protein (CRP) has a prognostic impact in head and neck squamous cell carcinoma (HNSCC). However, the acute phase reaction involves many other proteins depending on its inducing events, including various cytokines that can function as reaction ...
Helene Hersvik Aarstad, Svein Erik Emblem Moe, Øystein Bruserud, Stein Lybak, Hans Jørgen Aarstad, Tor Henrik Anderson Tvedt   +5 more
doaj   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Proliferating or interleukin 1-activated human vascular smooth muscle cells secrete copious interleukin 6 [PDF]

, 2014
The cells that make up blood vessel walls appear to participate actively in local immune and inflammatory responses, as well as in certain vascular diseases. We tested here whether smooth muscle cells (SMC) can produce the important inflammatory mediator
Libby, Peter, Loppnow, H
core   +1 more source

Common Food Emulsifiers Impair Epithelial Barrier Integrity and Trigger Pro‐Inflammatory Responses and IgE Production

Allergy, Volume 81, Issue 10, Page 3641-3658, October 2026.
Soy lecithin and DATEM, the two commonly used food emulsifiers introduced into many foods including peanut butter and puffed bread, in the 2000s, impair intestinal epithelial barrier integrity in human gut‐on‐a‐chip and induced pluripotent stem cell colon organoid models.
Duygu Yazici, Yuka Hayashi, Yagiz Pat, Jennifer Hotie, Mehmet Ali Balci, Sena Ardicli, Juan Felipe Lopez, Ozge Ardicli, Bingjie Zhao, Angel Maldonado, Can Zeyneloglu, Kenji Matsumoto, Manru Li, Beate Rückhert, Lihong Chang, Ismail Ogulur, Vahap Eldem, Raja Dhir, Mubeccel Akdis, Kari Nadeau, Oscar Palomares, Hideaki Morita, Cezmi A. Akdis   +22 more
wiley   +1 more source

A prominent role for the IL1 pathway and IL15 in susceptibility to chronic cavitary pulmonary aspergillosis.

, 2014
Chronic cavitary pulmonary aspergillosis (CCPA) is a progressive lung condition with a 10-30% annual mortality. Although overtly immunocompetent, some immunogenetic defect in patients is likely.
Smith, Nicola L D, Hankinson, J, Bowyer, P, Simpson, A; id_orcid, Denning, D W; id_orcid   +4 more
core   +1 more source

The Potential Role of Synovial T Cell Infiltration Following Knee Joint Injury in Symptoms and Progression to Osteoarthritis

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1863-1877, September 2026.
Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi, Miriam T. Jackson, Cindy C. Shu, Susan M. Smith, Margaret M. Smith, Sanaa Zaki, Hadrian Platzer, Nils Rosshirt, David Giangreco, Carla R. Scanzello, Christopher B. Little   +10 more
wiley   +1 more source

PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS [PDF]

Journal of IMAB, 2005
The research includes 84 patients with leptospirosis treated in Clinic at Infectious Diseases – Pleven. Mild course in 52,38%, moderate in 19,05%, and severe in 28,57% are established. Serum amylase level has been investigated in 37 cases.
Maria Atanasova, Galya I. Gancheva
doaj   +1 more source