Results 61 to 70 of about 18,106 (157)
PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS [PDF]
Journal of IMAB, 2005 The research includes 84 patients with leptospirosis treated in Clinic at Infectious Diseases – Pleven. Mild course in 52,38%, moderate in 19,05%, and severe in 28,57% are established. Serum amylase level has been investigated in 37 cases.
Maria Atanasova, Galya I. Gancheva
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British Journal of Pharmacology, Volume 183, Issue 17, Page 5389-5406, September 2026.Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi +10 more
wiley +1 more source
The Effects of Antifungal Azoles on Inflammatory Cytokine Production in Human Keratinocytes
Armaghane Danesh Bimonthly Journal, 2008 : Introduction & Objective: Azoles drugs are being used successfully in treatment of fungal infections. Recently, immunosuppressive effects of some of these agents have been reported. Keratinocytes, as the major cells of the skin, have an important role
K Zomorodian +3 more
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Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020 Our research focused on the role of immune mechanisms in diabetic foot ulcers development and impaired healing. A 3D skin culture system, as a relevant skin model, has proved valuable in investigating these mechanisms and is a useful tool to study ...
Mashkova M. A. +2 more
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Exploration, Volume 6, Issue 4, August 2026.Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li +14 more
wiley +1 more source
Patologìâ, 2020 The article deals with analyzing the influence of polymorphic variants of CYP19A1 [rs2414096, rs936306], ESR1 [rs2234693, rs9340799], RANKL [rs9594738, rs9594759], IL1 [rs1143627], IL6 [rs1800796] and IL10 [rs1800896] genes on malocclusion development in
O. V. Garmash, Ye. M. Riabokon
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Journal of Cellular Physiology, Volume 241, Issue 8, August 2026.ABSTRACT Cancer‐associated fibroblasts (CAFs) are key drivers of tumor progression. This study examined how three‐dimensional (3D) culture, hypoxia, and cancer‐derived soluble factors influence the transformation of human mesenchymal stem cells (hMSCs) into inflammatory CAFs (iCAFs). hMSCs from bone marrow, placenta, and chorion were cultured in 2D, in
Pimjai Chingsuwanrote +7 more
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, 2016 Resistance of tumors to antiangiogenic therapies is becoming increasingly relevant. We recently identified interleukin-1 (IL1), CXC receptors (CXCR)1/2 ligands, and transforming growth factor β (TGFβ) among the proinflammatory factors that were expressed
Aldo Scarpa +23 more
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Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.NF1‐LRD‐derived EVs suppress glioma cells' invasion and reprogram TAMs through the ADAM17‐TNFα‐ICAM‐1 signaling axis. These EVs reduce migration recruitment, enhance pro‐inflammatory polarization, and modulate key pathways, collectively reshaping the GBM TME. (Created with Biorender.com) ABSTRACT Extracellular vesicles (EVs) are increasingly recognized
Yuganthini Vijayanathan +13 more
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MedComm, Volume 7, Issue 7, July 2026.Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang +10 more
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