Results 91 to 100 of about 248,447 (288)

Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine [PDF]

, 2012
The neonatal Fc receptor (FcRn) transports maternal immunoglobulin (IgG) across epithelia to confer passive immunity to mammalian young. In newborn rodents, FcRn transcytoses IgG from ingested milk across the intestinal epithelium for release into the ...
Bjorkman, Pamela J., Huey-Tubman, Kathryn E., Ladinsky, Mark S.   +2 more
core   +2 more sources

Strain- and Sex-Dependent Circadian Changes in Abcc2 Transporter Expression: Implications for Irinotecan Chronotolerance in Mouse Ileum

PLoS ONE, 2011
Background ATP-binding cassette transporter abcc2 is involved in the cellular efflux of irinotecan. The drug is toxic for mouse ileum, where abcc2 is highly expressed.
A. Okyar, E. Piccolo, Constance Ahowesso, E. Filipski, Virginie Hossard, C. Guettier, R. La Sorda, N. Tinari, S. Iacobelli, F. Lévi   +9 more
semanticscholar   +1 more source

Imaging Right Iliac Fossa (RIF) pain [PDF]

, 2011
Abdominal pain is one of the most common causes for referral to the emergency department coming second only after chest pain. The RIF is the most common location for abdominal pain.
Vassallo, Pierre
core  

5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT₃ receptor resensitization due to Its subsequent release [PDF]

, 2014
The serotonergic synapse is dynamically regulated by serotonin (5-hydroxytryptamine (5-HT)) with elevated levels leading to the down-regulation of the serotonin transporter and a variety of 5-HT receptors, including the 5-HT type-3 (5-HT(3)) receptors ...
Aapro, Ahern, Amy Alexander, Andrew J. Samson, Bearcroft, Bertrand, Bertrand, Bhattacharyya, Boyd, Chanrion, Chen, Chen, Christopher Moffat, Christopher N. Connolly, Connolly, Craig, Faerber, Freeman, Galligan, Guthrie, Hagbom, Hanley, Hansen, Hothersall, Huang, Ilegems, J. Daniel Hothersall, Jiménez-Trejo, Karen A. Bollan, Kittler, Kondaurova, Lau, Lee, Linder, Liu, Liu, Lummis, McKinnon, Mercado, Minami, Mnie-Filali, Muchatuta, Niesler, Riad, Rojas, Schlag, Spiller, Stratz, Tao-Cheng, Turvill, Vikenes, Wade, Wesseldijk, Whalen, Yasuda   +54 more
core   +2 more sources

The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat [PDF]

, 2010
The effect of Pgp induction in rats by pregnenolone 16α-carbonitrile (PCN) (3 days, 35 mg/kg/d, p.o.) on digoxin pharmacokinetics and intestinal transport has been assessed.
Anna-Lena Ungell, Bauer, Britt-Marie Fihn, Constanze Hilgendorf, Englund, Harrison, Iain S. Haslam, Johan E. Karlsson, Lam, Nicholas L. Simmons, Noe, Read, Simon Lowes   +12 more
core   +2 more sources

Regional Differences in the Gut Microbiota and Gut-Associated Immunologic Factors in the Ileum and Cecum of Rats With Collagen-Induced Arthritis

Frontiers in Pharmacology, 2020
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic inflammation and a multifactorial etiology. We previously showed that gut microbiota dysbiosis in the rat ileum is involved in the development of collagen-induced arthritis
Huihui Xu, Jinfeng Cao, Xiaoya Li, Xiaoya Li, Xiangchen Lu, Xiangchen Lu, Ya Xia, Ya Xia, Danping Fan, Danping Fan, Hongyan Zhao, Dahong Ju, Cheng Xiao, Cheng Xiao   +13 more
doaj   +1 more source

SP-Sephadex equilibrium chromatography of bradykinin and related peptides: Application to trypsin-treated human plasma [PDF]

, 1977
An analytical method is deseribed for the separation of bradykinin, Lys-bradykinin, and Met-Lys-bradykinin by equilibrium chromatography on SP-Sephadex C-25 eluted in 0.02 Tris-HCl buffer, pH 8.10, 0.12 NaCl.
Camargo, Antonio C. M., Fink, Edwin, Greene, Lewis J., Reis, Marina L., Sampaio, Misako U.   +4 more
core   +1 more source

Quercetin and ibuprofen combination displayed anti-inflammatory effects and also extenuates the enteric neurons damage of arthritic rats [PDF]

Anais da Academia Brasileira de Ciências
This study aimed to investigate the antioxidant and anti-inflammatory properties of quercetin on the cellular components of the Enteric Nervous System in the ileum of rats with arthritis.
BRUNA THAIS DA SILVA, JULIANA VANESSA C. MARTINS-PERLES, GLEISON DAION P. BOSSOLANI, MARIANA M. LIMA, CAMILA C. SEHABER-SIERAKOWSKI, LUCAS B. GREMASCHI, JOÃO PAULO SILVEIRA E CUNHA, CIOMAR A. BERSANI-AMADO, JACQUELINE N. ZANONI   +8 more
doaj   +1 more source

Defining murine monocyte differentiation into colonic and ileal macrophages

eLife, 2020
Monocytes are circulating short-lived macrophage precursors that are recruited on demand from the blood to sites of inflammation and challenge. In steady state, classical monocytes give rise to vasculature-resident cells that patrol the luminal side of ...
Mor Gross-Vered, Sébastien Trzebanski, Anat Shemer, Biana Bernshtein, Caterina Curato, Gil Stelzer, Tomer-Meir Salame, Eyal David, Sigalit Boura-Halfon, Louise Chappell-Maor, Dena Leshkowitz, Steffen Jung   +11 more
doaj   +1 more source

Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells.

Journal of Clinical Investigation, 2003
IL-12 p40-related cytokines such as IL-12 p35/p40 heterodimer and IL-23 (p19/p40) are potent regulators of adaptive immune responses. Little is known, however, about the transcriptional regulation of the p40 gene in vivo.
C. Becker, S. Wirtz, M. Blessing, J. Pirhonen, D. Strand, Oliver Bechthold, J. Frick, P. Galle, I. Autenrieth, M. Neurath   +9 more
semanticscholar   +1 more source