Results 31 to 40 of about 724,062 (300)

An improved genome of the model marine alga Ostreococcus tauri unfolds by assessing Illumina de novo assemblies [PDF]

open access: yes, 2014
Background: Cost effective next generation sequencing technologies now enable the production of genomic datasets for many novel planktonic eukaryotes, representing an understudied reservoir of genetic diversity. O.
Blanc-Mathieu, Romain   +14 more
core   +6 more sources

The Personal Genome Project-UK, an open access resource of human multi-omics data [PDF]

open access: yes, 2019
Integrative analysis of multi-omics data is a powerful approach for gaining functional insights into biological and medical processes. Conducting these multifaceted analyses on human samples is often complicated by the fact that the raw sequencing output
Beck, Stephan   +12 more
core   +2 more sources

QQ-SNV: single nucleotide variant detection at low frequency by comparing the quality quantiles [PDF]

open access: yes, 2015
Background: Next generation sequencing enables studying heterogeneous populations of viral infections. When the sequencing is done at high coverage depth ("deep sequencing"), low frequency variants can be detected.
Aerssens, Jeroen   +7 more
core   +4 more sources

A Target Restricted Assembly Method (TRAM) for Phylogenomics [PDF]

open access: yes, 2010
While next generation sequencing technology can produce sequences covering the entire genome, assembly and annotation are still prohibitive steps for many phylogenomics applications.
Hugh M. Robertson   +2 more
core   +1 more source

Review on Illumina Sequencing Technology

open access: yesAustin Journal of Veterinary Science & Animal Husbandry, 2022
Illumina sequencing process utilizes biochemical methods to determine the correct order of nucleotide bases in a deoxyribonucleic acid. Macromolecule using sequencing-by-synthesis and reversible dye-terminators that enable the identification of single bases are introduced into DNA strands and used to determine the series of base pairs in DNA.
Emiyu K, Lelisa K
openaire   +1 more source

Illumina But With Nanopore: Sequencing Illumina libraries at high accuracy on the ONT MinION using R2C2 [PDF]

open access: yes, 2021
Abstract High-throughput short-read sequencing has taken on a central role in research and diagnostics. Hundreds of different assays exist today to take advantage of Illumina short-read sequencers, the predominant short-read sequencing technology available today.
Alexander Zee   +8 more
openaire   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Noninvasive prenatal testing in the general obstetric population: clinical performance and counseling considerations in over 85000 cases

open access: yesРепродуктивная эндокринология, 2017
The article contains the results of the research, which set two main goals. The first is the determination of the actual indicators of the effectiveness of noninvasive prenatal studies and the development of counseling tools about the predictability of a
P. A. Taneja   +3 more
doaj   +1 more source

A High-Throughput Method for Illumina RNA-Seq Library Preparation. [PDF]

open access: yes, 2012
With the introduction of cost effective, rapid, and superior quality next generation sequencing techniques, gene expression analysis has become viable for labs conducting small projects as well as large-scale gene expression analysis experiments. However,
Daniel H Chitwood   +8 more
core   +2 more sources

Rnaseq: Mrna To Illumina Library [PDF]

open access: yesProtocol Exchange, 2015
This protocol details the RNAseq sample preparation starting with mRNA and ending with quality control of finished libraries. This protocol was used specifically for virus mRNA samples related to ORFeome lab group.
Marcia Sanders   +2 more
openaire   +2 more sources

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