Results 151 to 160 of about 599,955 (287)

Comparative analysis of illumina and oxford nanopore sequencing platforms for 16S rRNA profiling of respiratory microbial communities

open access: yesScientific Reports
The respiratory microbiome plays a crucial role in health and disease, necessitating accurate characterization through high-throughput sequencing technologies.
Guillem Macip   +12 more
doaj   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti   +27 more
wiley   +1 more source

Full-length 16S rRNA gene sequencing by PacBio improves taxonomic resolution in human microbiome samples

open access: yesBMC Genomics
Background Sequencing variable regions of the 16S rRNA gene (≃300 bp) with Illumina technology is commonly used to study the composition of human microbiota.
Elena Buetas   +7 more
doaj   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

open access: yesAdvanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad   +6 more
wiley   +1 more source

Primed and ready: nanopore metabarcoding can now recover highly accurate consensus barcodes that are generally indel-free

open access: yesBMC Genomics
Background DNA metabarcoding applies high-throughput sequencing approaches to generate numerous DNA barcodes from mixed sample pools for mass species identification and community characterisation.
Jia Jin Marc Chang   +5 more
doaj   +1 more source

Systematic Genomic Surveillance of SARS-CoV-2 Virus on Illumina Sequencing Platforms in the Slovak Republic-One Year Experience. [PDF]

open access: yesViruses, 2022
Rusňáková D   +32 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy