Results 31 to 40 of about 7,843 (191)
Improved ventricular function during inhalation of PGI(2) aerosol partly relies on enhanced myocardial contractility [PDF]
, 2005 Inhaled prostacyclin (PGI(2)) aerosol induces selective pulmonary vasodilation. Further, it improves right ventricular ( RV) function, which may largely rely on pulmonary vasodilation, but also on enhanced myocardial contractility.
Thein, E. +12 more
core +1 more source
About choosing a vasodilator for vasoreactivity tests in heart transplant candidates
Патология кровообращения и кардиохирургия, 2015 The purpose of our prospective, consistent, non-randomized study was to analyze the results of vasoreactivity tests (VRT) performed with nitric oxide (NO) or inhaled Iloprost in heart transplant candidates.
А. Е. Баутин +7 more
doaj +1 more source
Inhaled Iloprost as a First-Line Therapy for Persistent Pulmonary Hypertension of the Newborn [PDF]
Neonatal Medicine, 2019 Purpose Persistent pulmonary hypertension of the newborn (PPHN) is a potentially fatal disease. Inhaled iloprost, a stable analogue of prostacyclin, has recently been used as a therapeutic option.
Seung Hyun Kim +3 more
doaj +1 more source
Revista Portuguesa de Pneumologia, 2012 Objective: Prostacyclin (PGI2) has been shown to inhibit the expression of pro-inflammatory and pro-fibrotic mediators in pulmonary fibrosis. In this study, we aimed to test the preventive effects of intraperitoneally administered iloprost, a stable PGI2
Z.A. Aytemur +7 more
doaj +1 more source
Extended Extracorporeal Support Utilizing Minimal Heparin and Iloprost (ZK36374)
, 2023 Iloprost (ZK36374), a prostacyclin analogue, has been shown to preserve platelet ultrastructure and reactivity. In an effort to reduce adverse platelet alterations, iloprost was utilized in three patients undergoing extended extra-corporeal support (EECS)
William B. Pelley +2 more
core +1 more source
Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry. [PDF]
Arthritis Care Res (Hoboken)Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
De Lorenzis E +77 more
europepmc +2 more sources
Therapeutic Advances in Respiratory Disease, 2019 Inhaled iloprost is a well-established medication to treat pulmonary arterial hypertension (PAH), a serious and potentially fatal disease of the pulmonary resistance vessels. The therapeutic administration of iloprost requires six to nine inhalations per
Tobias Gessler
doaj +1 more source
Iloprost for the treatment of frostbite: a scoping review
International Journal of Circumpolar Health, 2023 We performed a scoping review to identify the extent of the literature describing the use of iloprost in the treatment of frostbite. Iloprost is a stable synthetic analog of prostaglandin I2. As a potent inhibitor of platelet aggregation and vasodilator,
Josianne Gauthier +2 more
doaj +1 more source
, 2021 Background and Objectives: Frostbite is a freezing injury that can lead to amputation. Current treatments include tissue rewarming followed by thrombolytic or vasodilators.
Thierry Joffre +6 more
core +1 more source
Frontiers in Pharmacology, 2019 Background: Right ventricle (RV) function is among the most important prognostic factors for pulmonary arterial hypertension (PAH) patients. Inhaled iloprost, an inhaled member of the prostacyclin family, is effective for the treatment of severe PAH and ...
Jing-Hui Li +11 more
doaj +1 more source