Results 81 to 90 of about 12,109,427 (256)

Introduction of online adaptive radiotherapy for bladder cancer through a multicentre clinical trial (Trans-Tasman Radiation Oncology Group 10.01): Lessons learned

Journal of Medical Physics, 2013
Online adaptive radiotherapy for bladder cancer is a novel radiotherapy technique that was found feasible in a pilot study at a single academic institution.
Daniel Pham, Paul Roxby, Tomas Kron, Aldo Rolfo, Farshad Foroudi   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Current status of radiologist staffing, education and training in the 27 EU Member States

Insights into Imaging
This second article of a series of three publications summarises the radiologist situation regarding staffing as well as education and training as analysed by The European Union Radiation, Education, Staffing & Training (EU-REST) study.
Adrian P. Brady, Graciano Paulo, Boris Brkljacic, Christian Loewe, Martina Szucsich, Monika Hierath, on behalf of the European Society of Radiology   +6 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Post-Prostatectomy Image-Guided Radiotherapy: The Invisible Target Concept [PDF]

, 2017
International audienceIn the era of intensity-modulated radiation therapy, image-guided radiotherapy (IGRT) appears crucial to control dose delivery and to promote dose escalation while allowing healthy tissue sparing. The place of IGRT following radical
Crevoisier, Renaud,, Stephane Guérif, Stéphane Supiot, Renaud de Crevoisier, Crevoisier, Renaud, De, Mickael Antoine, Leduc, Nicolas, Supiot, Stéphane, Richaud, Pierre, Guerif, Stéphane, Florent Vilotte, Iriondo-Alberdi, Jone, Sargos, Paul, Laurence Thomas, Maxime Bobin, Vilotte, Florent, Antoine, Mickael, Pierre Richaud, Igor Latorzeff, Thomas, Laurence, Nicolas Leduc, Paul Sargos, Bobin, Maxime, Latorzeff, Igor, Jone Iriondo-Alberdi   +24 more
core   +1 more source

Guidelines and recommendations for radiologist staffing, education and training

Insights into Imaging
This article outlines the radiology-related staffing and education/training guidelines and recommendations developed by the European Commission-funded EU-REST (European Union Radiation, Education, Staffing & Training) project.
Adrian P. Brady, Christian Loewe, Boris Brkljacic, Graciano Paulo, Martina Szucsich, Monika Hierath, on behalf of the European Society of Radiology   +6 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Tumor motion in lung cancers: An overview of four-dimensional radiotherapy treatment of lung cancers

Asian Journal of Oncology, 2017
Most modern radiotherapy centers have adopted contouring based treatment. Sparing of the normal structures has been made more achievable than ever before by use of technologies such as Intensity Modulated Radiotherapy (IMRT) and Image guided radiotherapy
Anusheel Munshi, Nilaxi Khataniar, Tharmar Ganesh   +2 more
doaj   +1 more source

Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer [PDF]

, 2019
CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical ...
Scurr, E, Brown, G, White, IM, Oelfke, U, Wetscherek, A, Scurr, Erica, Bhide, S, Sohaib, A, Bhide, Shreerang, Wetscherek, Andreas, Nill, S, Dearnaley, D, Lalondrelle, S, Brown, Gina, Oelfke, Uwe, Dearnaley, David, Lalondrelle, Susan, White, Ingrid M, Nill, Simeon, Sohaib, Aslam   +19 more
core   +1 more source