Increased RPA1 gene dosage affects genomic stability potentially contributing to 17p13.3 duplication syndrome [PDF]
, 2011 A novel microduplication syndrome involving various-sized contiguous duplications in 17p13.3 has recently been described, suggesting that increased copy number of genes in 17p13.3, particularly PAFAH1B1, is associated with clinical features including ...
A Slupianek +50 more
core +3 more sources
Development of Spectral Imaging Cytometry
, 2023 AbstractSpectral flow cytometry is a new technology that enables measurements of fluorescent spectra and light scattering properties in diverse cellular populations with high precision. Modern instruments allow simultaneous determination of up to 40+ fluorescent dyes with heavily overlapping emission spectra, discrimination of autofluorescent signals ...
Ivan A, Vorobjev +2 more
openaire +2 more sources
Prognostic significance of DNA cytometry in cutaneous malignant lymphomas. [PDF]
, 1991 The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome.
Abmayr, Wolfgang +7 more
core +1 more source
Imaging cytometry without image reconstruction (ghost cytometry)
, 2019 Imaging and analysis of many single cells hold great potential in our understanding of heterogeneous and complex life systems and in enabling biomedical applications. We here introduce a recently realized image-free "imaging" cytometry technology, which we call ghost cytometry.
Ota, Sadao +4 more
openaire +2 more sources
Cellular Image Analysis and Imaging by Flow Cytometry [PDF]
Clinics in Laboratory Medicine, 2007 Imaging flow cytometry combines the statistical power and fluorescence sensitivity of standard flow cytometry with the spatial resolution and quantitative morphology of digital microscopy. The technique is a good fit for clinical applications by providing a convenient means for imaging and analyzing cells directly in bodily fluids.
Vidya Venkatachalam +4 more
openaire +3 more sources
Anticancer Activities of Meroterpenoids Isolated from the Brown Alga Cystoseira usneoides against the Human Colon Cancer Cells HT-29 [PDF]
, 2020 Colorectal cancer (CRC) is one of the most common types of cancers and a leading cause of cancer death worldwide. The current treatment for CRC mainly involves surgery, radiotherapy, and chemotherapy. However, due to the side effects and the emergence of
Calderón-Montaño, Jose M. +4 more
core +2 more sources
Frontiers in Microbiology, 2018 Extracellular phosphatase activity (PA) has been used as an overall indicator of P depletion in lake phytoplankton. However, detailed insights into the mechanisms of PA regulation are still limited, especially in the case of acid phosphatases.
Jaroslav Vrba +6 more
doaj +1 more source
CA19-9 as a Potential Target for Radiolabeled Antibody-Based Positron Emission Tomography of Pancreas Cancer. [PDF]
, 2011 Introduction. Sensitive and specific imaging of pancreas cancer are necessary for accurate diagnosis, staging, and treatment. The vast majority of pancreas cancers express the carbohydrate tumor antigen CA19-9. The goal of this study was to determine the
Girgis, Mark D +5 more
core +4 more sources
Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells [PDF]
, 2019 Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired.
Braeckmans, Kevin +10 more
core +2 more sources
Image3C, a multimodal image-based and label-independent integrative method for single-cell analysis
eLife, 2021 Image-based cell classification has become a common tool to identify phenotypic changes in cell populations. However, this methodology is limited to organisms possessing well-characterized species-specific reagents (e.g., antibodies) that allow cell ...
Alice Accorsi +5 more
doaj +1 more source