Results 71 to 80 of about 285,255 (319)

Automation of flow cytometry data analysis with elastic image registration. [PDF]

Sci Rep
Cell populations in flow cytometry are typically identified via visual manual gating, a time-consuming and error-prone approach to select subpopulations based on expression of cellular markers.
Irvine A, Moustafa MM, Patel S, Patel A, Hardardottir L, Delvecchio F, Foreman T, Oak J, Bornheimer SJ, Cimbro R.   +9 more
europepmc   +2 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Diagnostic DNA-Flow- vs. -Image-Cytometry in Effusion Cytology

Analytical Cellular Pathology, 2002
Aims: To determine the sensitivity and specificity of flow‐ and image‐cytometry for the detection of DNA‐aneuploidy as a marker for malignant cells in effusions.
Helma Motherby, Natalia Pomjanski, Mary Kube, Alexandra Boros, Thomas Heiden, Bernhard Tribukait, Alfred Böcking   +6 more
doaj   +1 more source

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis [PDF]

, 2007
Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene initiate a majority of colorectal cancers. Acquisition of chromosomal instability is an early event in these tumors.
Clarke, Alan, Dikovskaya, Dina, Jamieson, Thomas J., Kroboth, Karin, Meniel, Valerie, Nathke, Inke S., Newton, Ian P., Oakley, Abigail, Sansom, Owen, Schiffmann, David   +9 more
core   +4 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

SEM–Raman image cytometry of cells

The Analyst, 2018
Hybrid SEM–Raman microscopy to distinguish individual human cells.
A. Enciso-Martinez, F. J. Timmermans, A. Nanou, L. W. M. M. Terstappen, C. Otto   +4 more
openaire   +3 more sources

Biophotonic Tools in Cell and Tissue Diagnostics. [PDF]

, 2007
In order to maintain the rapid advance of biophotonics in the U.S. and enhance our competitiveness worldwide, key measurement tools must be in place. As part of a wide-reaching effort to improve the U.S.
Brownstein, Michael, Dowell, ML, Gaigalas, AK, Hoffman, Robert A, Hwang, JC, Levenson, Richard, Milner, Thomas E, White, GS, Williams, PA   +8 more
core   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Mechanisms of nuclear content loading to exosomes. [PDF]

, 2019
Exosome cargoes are highly varied and include proteins, small RNAs, and genomic DNA (gDNA). The presence of gDNA suggests that different intracellular compartments contribute to exosome loading, resulting in distinct exosome subpopulations.
Burks, Jared K, Clise-Dwyer, Karen, De Hoff, Peter, Laurent, Louise C, Liu, Jinsong, Morey, Robert, O'Halloran, Theresa J, Oliphint, Paul Allen, Roszik, Jason, Song, Xingzhi, Sood, Anil K, Villar-Prados, Alejandro, Yokoi, Akira, Zhang, Jianhua   +13 more
core  

Detection and quantification of viable airborne bacteria and fungi using solid-phase cytometry [PDF]

, 2009
This protocol describes the use of solid-phase cytometry for the enumeration of airborne bacteria and fungi. In contrast with conventional methods, accurate results can be obtained in real time, especially for air samples with low numbers of ...
Coenye, Tom, Nelis, Hans, Vanhee, Lies
core   +1 more source