Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog. [PDF]
, 2019 BackgroundEvolution of indolent to aggressive lymphoma has been described in dogs but is difficult to distinguish from the de novo development of a second, clonally distinct lymphoma.
Bienzle, Dorothee +6 more
core +1 more source
Advanced Functional Materials, EarlyView.Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro +7 more
wiley +1 more source
MAUI (MBI Analysis User Interface)-An image processing pipeline for Multiplexed Mass Based Imaging.
PLoS Computational Biology, 2021 Mass Based Imaging (MBI) technologies such as Multiplexed Ion Beam Imaging by time of flight (MIBI-TOF) and Imaging Mass Cytometry (IMC) allow for the simultaneous measurement of the expression levels of 40 or more proteins in biological tissue ...
Alex Baranski +6 more
doaj +1 more source
Multilevel analysis of nuclear dynamics in lamin perturbed fibroblasts [PDF]
, 2010 The nuclear lamina provides structural support to the nucleus and has a central role in defining nuclear organization. Defects in its filamentous constituents, the lamins, lead to a class of diseases collectively referred to as laminopathies.
Broers, Jos +7 more
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Insights into the regulation of brain metastasis by natural killer cells using single-cell RNA sequencing and imaging mass cytometry [PDF]
, 2023 Timothy P McMullen +5 more
openalex +1 more source
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Advanced Functional Materials, EarlyView.Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh +3 more
wiley +1 more source
Heterogeneity in pure microbial systems: experimental measurements and modeling [PDF]
, 2017 Cellular heterogeneity influences bioprocess performance in ways that until date are not completely elucidated. In order to account for this phenomenon in the design and operation of bioprocesses, reliable analytical and mathematical descriptions are ...
González-Cabaleiro, Rebeca +4 more
core +2 more sources
Decoding the structural and cellular composition of the tumor microenvironment in multiple human cancers using Imaging Mass Cytometry [PDF]
, 2023 Thomas D. Pfister +5 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source
Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. [PDF]
, 2018 Tissue-specific autoimmunity occurs when selected antigens presented by susceptible alleles of the major histocompatibility complex are recognized by T cells.
Anderson, Mark S +8 more
core