Results 101 to 110 of about 5,090,386 (280)

Pushing the Limits of Cell Segmentation Models for Imaging Mass Cytometry

open access: yes2024 IEEE International Symposium on Biomedical Imaging (ISBI)
Imaging mass cytometry (IMC) is a relatively new technique for imaging biological tissue at subcellular resolution. In recent years, learning-based segmentation methods have enabled precise quantification of cell type and morphology, but typically rely on large datasets with fully annotated ground truth (GT) labels.
Kimberley M. Bird   +3 more
openaire   +4 more sources

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

open access: yesAdvanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Imaging Mass Cytometry Compensation Slide Acquisition v1 [PDF]

open access: yes, 2020
This SOP describes the slide acquisition for spill-over correction of Imaging Mass Cytometry experiments. The protocol makes use of the compensation slide, which was prepared previously following the SOP: “HuBMAP_Protocol_3_Compensation_Slide_Preparation.pdf” to measure each conjugated antibody individually and to record all observed spill-over.
Michelle Daniel, Marda Jorgensen
openaire   +1 more source

Mass observation / by Mass Observation.

open access: yes, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core  

Multifunctional Thiolated Hyaluronic Acid‐graft‐PEDOT Dressing With Antifouling, On‐Demand Drug Delivery and Electrical Stimulation for Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
A multifunctional P(EDOT‐co‐EDOT‐g‐THA) dressing acts as a dynamic biointerface integrating antifouling capability, on‐demand drug delivery, and electrical stimulation. It achieves electrochemically triggered thiolated hyaluronic acid (THA) release while modulating cellular responses for wound healing application.
Jingwen Yang   +8 more
wiley   +1 more source

Cutting FFPE Sections for Imaging Mass Cytometry v1 [PDF]

open access: yes, 2020
FFPE block are cut into thin sections.
Marda Jorgensen, Michelle Daniel
openaire   +1 more source

Multispectral imaging flow cytometry reveals distinct frequencies of γ-H2AX foci induction in DNA double strand break repair defective human cell lines [PDF]

open access: yes, 2011
Copyright @ 2012 International Society for Advancement of Cytometry. The article can be accessed from the links below.This article has been made available through the Brunel Open Access Publishing Fund.The measurement of γ-H2AX foci induction in cells ...
Bourton, EC   +13 more
core   +1 more source

Experimental and Data Analysis Considerations for Three-Dimensional Mass Spectrometry Imaging in Biomedical Research

open access: yes, 2021
Mass spectrometry imaging (MSI) enables the visualization of molecular distributions on complex surfaces. It has been extensively used in the field of biomedical research to investigate healthy and diseased tissues.
Balluff, B.   +3 more
core   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

open access: yesAdvanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu   +7 more
wiley   +1 more source

A New Method and Mass Spectrometer Design for TOF-SIMS Parallel Imaging MS/MS

open access: yes, 2016
We report a method for the unambiguous identification of molecules in biological and materials specimens at high practical lateral resolution using a new TOF-SIMS parallel imaging MS/MS spectrometer.
Heeren, Ron M. A.   +6 more
core   +1 more source

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