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Repository for high-resolution imaging mass cytometry data
Whipman, James, Bollhagen, Alina
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Mass Cytometry, Imaging Mass Cytometry, and Multiplexed Ion Beam Imaging Use in a Clinical Setting
Clinics in Laboratory Medicine, 2021Mass cytometry (MC), imaging mass cytometry (IMC), and multiplexed ion beam imaging (MIBI) represent a new generation of tools to understand increasingly complex systems. Although these technologies differ in their intended applications, with MC being most similar to flow cytometry, and IMC/MIBI being similar to immunohistochemistry, they all share a ...
Raymond Devine
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Cytometry Part A: the Journal of the International Society for Analytical Cytology, 2017 AbstractImaging Mass Cytometry (IMC) is an expansion of mass cytometry, but rather than analyzing single cells in suspension, it uses laser ablation to generate plumes of particles that are carried to the mass cytometer by a stream of inert gas. Images reconstructed from tissue sections scanned by IMC have a resolution comparable to light microscopy ...
Iram Siddiqui
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Ruthenium counterstaining for imaging mass cytometry
Journal of Pathology, 2018AbstractImaging mass cytometry is a novel imaging modality that enables simultaneous antibody‐based detection of >40 epitopes and molecules in tissue sections at subcellular resolution by the use of isotopically pure metal tags. Essential for any imaging approach in which antigen detection is performed is counterstaining, which reveals the overall ...
Bernd Bodenmiller +2 more
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Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry [PDF]
Cell Systems, 2018 ISSN:2405 ...
Vito R T Zanotelli +2 more
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Automated Cell Phenotyping for Imaging Mass Cytometry
2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2022Imaging mass cytometry (IMC) is a new advancement in tissue imaging that is quickly gaining wider usage since its recent launch. It improves upon current tissue imaging methods by allowing for a significantly higher number of proteins to be imaged at once on a single tissue slide. For most analyses of IMC data, determining the phenotype of each cell is
Sindhura Thirumal +4 more
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Imaging Mass Cytometry in Immuno-Oncology
2023In situ profiling of the tumor-immune microenvironment (TiME) requires the ability to co-localize and detect multiple proteins simultaneously. Imaging mass cytometry (IMC), using the Hyperion™ imaging system is a novel multiplex imaging modality that currently enables detection of up to 50 markers on fixed tissues at subcellular resolution and thus has
Tiziana, Cotechini +2 more
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