Results 121 to 130 of about 7,247 (206)

Thiazolidinones: novel insights from microwave synthesis, computational studies, and potentially bioactive hybrids. [PDF]

Beilstein J Org Chem
Martinho LA, Praciano VHJG, Matos GDR, Gatto CC, Andrade CKZ.   +4 more
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Imidazo[1,2-a]pyridines: Promising Drug Candidate for Antitumor Therapy

Current Topics in Medicinal Chemistry, 2016
Imidazo[1,2-a]pyridine has been shown to be an important biologically active moiety. This review is a compilation of the scattered output of results of the anticancer activities of the imidazo[1,2-a]pyridine system since 2001, which have been classified as inhibition of CDK, VEGFR, PI3K, EGFR, RGGT etc.
Richa, Goel, Vijay, Luxami, Kamaldeep, Paul   +2 more
openaire   +3 more sources

Recent Progress in the Pharmacology of Imidazo[1,2-a]pyridines

Mini-Reviews in Medicinal Chemistry, 2007
Imidazo[1,2-a]pyridine is a bicyclic system with a bridgehead nitrogen atom, of growing interest in medicinal chemistry. The paper deals with the recent progress realised in the comprehension of the pharmacological properties of this scaffold. From the many imidazo[1,2-a]pyridine analogues described in the literature, those discussed herein will be ...
Cécile, Enguehard-Gueiffier, Alain, Gueiffier   +1 more
openaire   +3 more sources

Synthesis of imidazo[1,2-a]pyridines: a decade update

Chemical Communications, 2015
Here we describe the various strategies for the synthesis of imidazo[1,2-a]pyridines.
Avik Kumar, Bagdi, Sougata, Santra, Kamarul, Monir, Alakananda, Hajra   +3 more
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Multicomponent Synthesis of Imidazo[1,2‐a]pyridines Using Catalytic Zinc Chloride.

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Amanda L. Rousseau, Pulane Matlaba, Christopher J. Parkinson   +2 more
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Diastereoisomeric Imidazo[1,2-a]pyridines

Mendeleev Communications, 1995
The axially chiral ketone 1 and its methyl derivative 2 have been reduced with sodium borohydride to the corresponding diastereoisomeric alcohols 3 and 4 .
Richard Kubík, Jan Němeček, Stanislav Böhm, Martin Hradilek, Josef Kuthan   +4 more
openaire   +1 more source

Imidazo[1,2-a]pyridines with potent activity against herpesviruses

Bioorganic & Medicinal Chemistry Letters, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kristjan S, Gudmundsson, Brian A, Johns
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Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines

Bioorganic & Medicinal Chemistry, 2008
The key dinitrile intermediates 4a-d were synthesized by reaction of phenacyl bromide 1 and the appropriate 2-amino-5-bromopyridines to yield 3a-d. Suzuki coupling of 3a-d with 4-cyanophenylboronic acid yielded the 2,6-bis(4-cyanophenyl)-imidazo[1,2-a]pyridine derivatives 4a-d. The bis-amidoximes 5a-d, obtained from 4a-d by the action of hydroxylamine,
Mohamed A, Ismail, Reem K, Arafa, Tanja, Wenzler, Reto, Brun, Farial A, Tanious, W David, Wilson, David W, Boykin   +6 more
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ChemInform Abstract: Diastereoisomeric Imidazo(1,2‐a)pyridines.

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
R. KUBIK, J. NEMECEK, S. BOEHM, M. HRADILEK, J. KUTHAN   +4 more
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Design, synthesis and mechanistic studies of novel imidazo[1,2-a]pyridines as anticancer agents.

Bioorganic chemistry (Print), 2022
Herein, the design, synthesis and mechanistic study of five series of imidazo[1,2-a]pyridines 8a-d, 9a-f, 11a-c, 12a-d and 14a-d as anticancer agents were discussed.
Ahmed S. Ismael, Noha H Amin, Mohammed T. El-Saadi, H. Abdel-Rahman   +3 more
semanticscholar   +1 more source