Results 131 to 140 of about 7,247 (206)

Synthesis of imidazo[1,2- a] pyridines directly from methyl or methylene ketones. iodination of imidazo[1,2-a] pyridines

Chemistry of Heterocyclic Compounds, 1976
Imidazo[1,2-a]pyridines were obtained by direct reaction of acetophenone, propiophenone, and their furan analogs and ring-substituted derivatives with an equimolar amount of iodine and and excess 2-aminopyridine or its substituted derivatives. The effect of substituents in the ketones and 2-aminopyridine, the reagent molar ratios, the character of the ...
N. O. Saldabol, S. A. Giller
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Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents

Current Topics in Medicinal Chemistry, 2016
Imidazo[1,2-a]pyridine is one of the most potential bicyclic 5-6 heterocyclic rings that is recognized as a "drug prejudice" scaffold due to its broad range of applications in medicinal chemistry such as anticancer, antimycobacterial, antileishmanial, anticonvulsant, antimicrobial, antiviral, antidiabetic, proton pump inhibitor, insecticidal activities.
Aakash, Deep, Richa Kaur, Bhatia, Ramanjot, Kaur, Sanjiv, Kumar, Upendra Kumar, Jain, Harinder, Singh, Sandeep, Batra, Dinesh, Kaushik, Pran Kishore, Deb   +8 more
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ChemInform Abstract: Imidazo(1,2‐a)pyridines. Part 2. Ozonolysis of Imidazo(1,2‐a)pyridines and Synthesis of Cardiotonic Agents.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. YAMANAKA, S. SUDA, N. YONEDA, H. OHHARA   +3 more
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Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations.

Bioorganic chemistry (Print)
The current study investigates the anticancer and VEGFR-2 inhibitory activities of 16 novel indolinone-grafted imidazo[2,1-b]thiazole and imidazo[1,2-a]pyridine derivatives (6a-h and 10a-h).
Mahmoud S. Elkotamy, Mohamed K. Elgohary, Sara T. A. Al-Rashood, Hadia Almahli, Wagdy M. Eldehna, Hatem A. Abdel-Aziz   +5 more
semanticscholar   +1 more source

Organotin(IV) complexes with imidazo[1,2-a]pyridines

Polyhedron, 2014
Abstract The three-components reaction of dimethyltin dibromide with imidazo[1,2-a]pyridine and allyl bromide in ethanol affords an ionic complex, bis(1-allylimidazo[1,2-a]pyridinium) dimethyltetrabromostannate(II). X-ray crystal structure analysis of the complex reveals the tin atom to be hexacoordinated, forming a dianion.
Rati Agrawal, Varsha Goyal, Raakhi Gupta, Raghavaiah Pallepogu, Ramesh Kotikalapudi, Peter G. Jones, Raj K. Bansal   +6 more
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ChemInform Abstract: Photoisomerization of Imidazo(1,2‐a)pyridines.

ChemInform, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
R. KUBIK, S. BOEHM, V. HAVLICEK, J. KUTHAN   +3 more
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Discovery of imidazo[1,2-a]pyridines as potent MCH1R antagonists

Bioorganic & Medicinal Chemistry Letters, 2009
A series of imidazo[1,2-a]pyridine derivatives was identified and evaluated for MCH1R binding and antagonistic activity. Introduction of a methyl substituent at the 3-position of imidazo[1,2-a]pyridine provided compounds with a significant improvement in MCH1R affinity.
Hiroyuki, Kishino, Minoru, Moriya, Shunji, Sakuraba, Toshihiro, Sakamoto, Hidekazu, Takahashi, Takao, Suzuki, Ryuichi, Moriya, Masahiko, Ito, Hisashi, Iwaasa, Norihiro, Takenaga, Akane, Ishihara, Akio, Kanatani, Nagaaki, Sato, Takehiro, Fukami   +13 more
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Synthesis of Imidazo[1,2-a]pyridine Derivatives as Antiviral Agents

Arzneimittelforschung, 2011
The synthesis and antiviral activity of original dibromoimidazo[1,2-a]pyridines bearing a thioether side chain are reported. Molecular modeling was used to identify biophoric structural patterns that are common to 16 compounds. Structure-activity relationship (SAR) studies identified hydrophobicity (logP) as the most important factor for activity. From
S, Mavel, J L, Renou, C, Galtier, R, Snoeck, G, Andrei, J, Balzarini, E, De Clercq, A, Gueiffier   +7 more
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Reactions of 1‐Substituted Benz[4,5]imidazo[1,2‐a]pyridines.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Yu. M. Volovenko, V. V. Ivanov, A. O. Pushechnikov   +2 more
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Visible-Light-Promoted and EDA Complex-Driven [4 + 2] Annulation for the Construction of Naphtho[1',2':4,5]imidazo[1,2-a]pyridines.

Organic Letters
A green visible-light-promoted and electron donor-acceptor (EDA) complex-driven synthetic strategy for the construction of value-added naphtho[1',2':4,5]imidazo[1,2-a]pyridines from 2-arylimidazo[1,2-a]pyridines with Z-α-bromocinnamaldehydes has been ...
Wanting Feng, Ziren Chen, Fei Xue, Zuozhi Zhang, Bin Wang, Yonghong Zhang, Yu Xia, Weiwei Jin, Shaofeng Wu, Chenjiang Liu   +9 more
semanticscholar   +1 more source