Results 111 to 120 of about 184,143 (305)

Imidazole-Functionalized Porous Graphene Oxide Nanosheets Loaded with Palladium Nanoparticles for the Oxidative Amidation of Aldehydes [PDF]

open access: yes
In this study, 1-(3-aminopropyl)­imidazole-functionalized porous graphene oxide nanosheets (GONs) decorated with palladium nanoparticles (Pd NPs; size, ∼11 nm) have been developed.
Padmini Gupta (9953141)   +4 more
core   +1 more source

SYNTHESIS OF METAL-ORGANIC (COMPLEXES) COMPOUNDS COPPER(II)-IMIDAZOLE FOR ANTIVIRAL HIV CANDIDATE

open access: yesIndonesian Journal of Tropical and Infectious Disease, 2016
The human immunodeficiency virus (HIV) is viruses known as rotaviruses. Potential target for therapeutic is reverse transcriptase (RT), possesses an RNA dependent DNA polymerase, DNA-dependent DNA polymerase and ribonuclease H fuctions.
Teguh Hari Sucipto, Fahimah Martak
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng   +9 more
wiley   +1 more source

Degradation Kinetics of Clavulanic Acid in Fermentation Broths at Low Temperatures

open access: yesAntibiotics, 2019
Clavulanic acid (CA) is a β-lactam antibiotic inhibitor of β-lactamase enzymes, which confers resistance to bacteria against several antibiotics.
David Gómez-Ríos   +4 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He   +9 more
wiley   +1 more source

Structure of imidazole and imidazole-derivatives with atom numbering. [PDF]

open access: yes, 2018
The unsubstituted imidazole group is shown in the center. Other important imidazole molecules are shown: histidine (2-amino-3-(1H-imidazol-4-yl), adenine (9H–purin-6-amine), adenosine monophosphate (N9-ribosyl-adenine), and N6-ribosyladenine (which ...
Antonio Lazcano (583538)   +2 more
core   +1 more source

Diethyl 4-(4-chloro-2-propyl-1H-imidazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate monohydrate

open access: yesIUCrData, 2018
In the title hydrate, C19H26ClN3O4·H2O, the imidazole ring is nearly perpendicular [dihedral angle = 89.5 (1)°] to the dihydropyridine moiety. The propyl and one of the ethyl groups are disordered over two resolved sets of sites [occupancy factors 0.524 (
Kedila Rasheeda   +5 more
doaj   +1 more source

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman   +7 more
wiley   +1 more source

Imidazole concordance. [PDF]

open access: yes, 2013
Antigen solutions (50 nM) with and without imidazole (25 mM) were used to coat plates, and AAbs in cohort 1 serum samples were detected by ELISA (HTPA): a) an example of a concordance plot between the OD signal for p53 BirA with and without imidazole; b)
Caroline J. Chapman (110960)   +7 more
core   +1 more source

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