Results 191 to 200 of about 339,340 (383)

Ligand‐Protein Interactions in Imidazole and 1,2,4‐Triazole Complexes of Methaemoglobin from Chironomus plumosus [PDF]

, 1967
Peter Mohr, W Scheler, Hans Schumann, K. Müller   +3 more
openalex   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Heats of Hydrolysis of N-Acetyl Imidazole and Butyl Acetamide in Aqueous Solution. [PDF]

, 1962
Ingemar Wadsö, Cyrill Brosset, Madeleine Seleborg, K. Motzfeldt, Olof Theander, H. Flood   +5 more
openalex   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang, Xueying Wang, Shanhong Lu, Yan Gao, Gangcai Zhu, Guo Li, Zongnan Yu, Junwei Hou, Helei Yan, Wenhui Yuan, Xin Zhang, Mien‐Chie Hung, Zhifeng Liu, Yong Liu   +13 more
wiley   +1 more source

Imidazole Compounds Accumulated by Purine Mutants of Neurospora crassa

, 1961
Harris D. Bernstein
openalex   +1 more source

Detection by paper chromatography of imidazoles, including hydantoin-5-propionic acid, in urine after histidine dosage [PDF]

, 1965
John Middleton
openalex   +1 more source

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

Advanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu, Shumin Li, Jiaji Wu, Shumin Xu, Mo Shen, Chenyang Wang, Lundqvist Andreas, Jianghao Yu, Zhiyong Xu, Yueli Shi, Nana Liu, Yunke Yang, Jiangnan Zhao, Ying Yang, Pingli Wang, Peng Yi, Jin Cheng, Junhui Sun, Mengshu Li, Peng Xiao, Kai Wang   +20 more
wiley   +1 more source

SYNTHESIS OF IMIDAZOLE

A simple approach was used to prepare concentrated nitric acid supported on nano silica (HNO3@nanoSiO2). The synthetic powder was used as an efficient catalytic system for the synthesis of different 2,4,5-trisubstituted imidazoles in good to outstanding yields under solvent-free conditions at 100 C. Furthermore, 1,2,4,5-tetrasubstituted imidazoles have
openaire   +1 more source

Engineering Electron Transfer Flux between Cytochrome P450 Enzyme and P450 Reductase to Enhance Serotonin Production in Escherichia Coli

Advanced Science, EarlyView.
The electron transfer flux in CPR‐P450 catalytic system is systematically engineered through: i) enhancing electron transfer rate by redesigning the putative electron transfer pathway of CPR; ii) improving electron‐receiving rate by evolving the heme domain of tryptophan‐5‐hydroxylase (T5H); iii) enlarging electron supply by fine‐tuning NADPH synthesis.
Wenzhao Xu, Pengling Wei, Lirong Chen, Ling Gao, Xiaole Xia   +4 more
wiley   +1 more source

Retraction of "New Smart Magnetic Ionic Liquid Nanocomposites Based on Chemically Bonded Imidazole Silica for Water Treatment". [PDF]

ACS Omega
Sabeela NI, Almutairi TM, Al-Lohedan HA, Ezzat AO, Atta AM.   +4 more
europepmc   +1 more source