Results 201 to 210 of about 288,362 (336)
USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang+9 more
wiley +1 more source
Theoretical Insights into the Impact of Pyrrole and Imidazole Substituents on the BODIPY Chromophore. [PDF]
Piękoś P+4 more
europepmc +1 more source
Synthesis of Imidazoles by Catalytic Dehydrogenation of Imidazolines
N. SAWA
openalex +2 more sources
Protonation of the Radical-anions of Nitro-imidazole Radiosensitizers and the Formation of Radical-adducts [PDF]
Peter Wardman
openalex +1 more source
Mutation of Surface Histidines in \u3ci\u3eHaemophilus influenzae\u3c/i\u3e Carbonic Anhydrase to Enable Purification by Metal Affinity Chromatography [PDF]
Cornely, Kathleen, Scola, Shelby E.
core +1 more source
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie+9 more
wiley +1 more source
Rab11 Binding Promotes the p14 FAST Protein-Induced Syncytium Formation. [PDF]
Lin S+7 more
europepmc +1 more source
Pyrrole Hydrogen Ionization of Imidazole Derivatives in Metal Ion Complexes and Carbonic Anhydrase [PDF]
R. Bruce Martin
openalex +1 more source
To address the problem of off‐target movement and low bioavailability of pesticides, two anisotropic supramolecular building units (BiTA18@β‐CD and BiTA18@γ‐CD) have been invented that can self‐assemble into nano‐sized hexagonal cuboids on the rice microcrystalline matrix. This manipulation realizes the enhanced utilization of bactericides for rice and
Run Yang+4 more
wiley +1 more source