Results 271 to 280 of about 339,340 (383)
A Novel Protein Purification Approach Using Elastin-Like Polypeptides (ELP) With His-Tag Assistance. [PDF]
Bio ProtocChae YK, Shin HB.
europepmc +1 more source
Advanced Science, EarlyView.Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du +7 more
wiley +1 more source
Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes. [PDF]
ChembiochemDécout JL, Maurel MC.
europepmc +1 more source
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Advanced Science, EarlyView.Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu +7 more
wiley +1 more source
Crystal structure and Hirshfeld surface analysis of 1-[2-(2-chloro-eth-oxy)eth-yl]-2-methyl-4-nitro-1<i>H</i>-imidazole. [PDF]
Acta Crystallogr E Crystallogr CommunMohan Kumar TM +5 more
europepmc +1 more source
Advanced Science, EarlyView.MRC is a live‐cell method enabling visualization of protein–protein interactions and biomolecular condensates. It supports multi‐protein colocalization, binding analysis, and programmable condensate manipulation, providing a versatile platform for studying dynamic cellular organization.
Lei Peng +8 more
wiley +1 more source
An Overview of Glutaminyl Cyclase as a Promising Drug Target for Alzheimer's Disease. [PDF]
BiomedicinesMadhusudhana R, Boyle E, Cen Y.
europepmc +1 more source