Results 281 to 290 of about 339,340 (383)

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

Advanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou   +10 more
wiley   +1 more source

Hybrid <i>Bis</i>-(Imidazole/Benzimidazole)-Pyridine Derivatives with Antifungal Activity of Potential Interest in Medicine and Agriculture via Improved Efficiency Methods. [PDF]

Pharmaceuticals (Basel)
Balaes T, Mangalagiu V, Antoci V, Amariucai-Mantu D, Diaconu D, Mangalagiu II.   +5 more
europepmc   +1 more source

Preparation of Spin-Labeled Phosphoroamidates in High Yield Using Imidazole as the Transfer Agent

, 1977
G. SOSNOVSKY, M. KONIECZNY
openalex   +2 more sources

Bioinspired Brush Reinforced Solid Slippery Coatings for Marine Photovoltaic Protection

Advanced Science, EarlyView.
Plant cuticles exhibit exceptional liquid repellency and self‐healing properties, providing a novel strategy for the multifunctional self‐cleaning materials. A plant‐inspired solid slippery surface (PI‐SSS) based on surface‐grafted poly(ionic liquid) brushes and lubricating copolymer via ion‐dipole interactions are introduced, effectively protecting ...
Ling Yin, Runxiang Tan, Junyi Han, Jianing Wang, Jianjun Cheng, Daheng Wu, Tao Zhang, Liping Wang   +7 more
wiley   +1 more source

Time-Dependent Particle-Breaking Hartree-Fock Model for Electronically Open Molecules. [PDF]

J Phys Chem A
Pedersen J, Sannes BS, Paul Née Matveeva R, Coriani S, Høyvik IM.   +4 more
europepmc   +1 more source

Mortalin and PINK1/Parkin‐Mediated Mitophagy Represent Ovarian Cancer‐Selective Targets for Drug Development

Advanced Science, EarlyView.
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra, Justin Garland, Rajani Rai, Donghua Zhao, Charuksha Walgama, Sadagopan Krishnan, Andrew T. Long, Tongzu Liu, Laura Adhikari, Doris M. Benbrook   +9 more
wiley   +1 more source

Integrated computational and experimental identification of <i>N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide</i> as a potent and selective TIM-3 inhibitor for NSCLC immunotherapy. [PDF]

Front Chem
Ying X, Lou Y, Wu Y, Hu W.
europepmc   +1 more source

Confinement‐Induced Metastable Supramolecular Assembly: Dynamic Built‐in Electric Field Driving Deep Mineralization of Organic Pollutants

Advanced Science, EarlyView.
Utilizing the 2D confined space of layered double hydroxide (LDH), living supramolecular assembly (LSA) are successfully prepared with smaller intermolecular distances than in crystals. The IEF enhancement value can reach 11.8 times, which induces a charge separation efficiency of 71.52%.
Xiaoqing Cao, Kaixiang Liang, Feifei Peng, Xianggui Kong, Wenying Shi   +4 more
wiley   +1 more source

Protocol for evaluating the impact of non-coding variants on transcription factor binding and gene expression. [PDF]

STAR Protoc
Peña-Martínez EG, Rodríguez-Ríos JM, Messon-Bird JL, Barreiro-Rosario AC, Velázquez-Roig R, Rivera-Madera A, Peterson-Peguero EA, Rodríguez-Martínez JA.   +7 more
europepmc   +1 more source

Zwitterion‐Stabilized Superlattices and Frank‐Kasper Phases in Charged Block Copolymers for Mechanically Robust Dielectric Soft Materials

Advanced Science, EarlyView.
Superlattices formed by the co‐assembly of acid‐functionalized block copolymers and zwitterions exhibit tunable morphologies, transitioning from lamellae to cylinders to Frank‐Kasper phases. Zwitterion interfacial localization enhances dielectric constant, mechanical strength, and thermal stability, making these materials promising for soft electronics
Jaemin Min, Hojun Lee, Moon Jeong Park
wiley   +1 more source