Results 111 to 120 of about 65,673 (219)
Listeria are Gram-negative intracellular foodborne pathogens that can cause invasive infections with high mortality rates. In this work, the antibacterial activity of ten essential oils, infusion extracts, and decoction extracts of some medicinal plants ...
Abdul-Raouf Al-Mohammadi +5 more
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An overview of the pharmacology of imipenem/cilastatin
Imipenem is the first clinically available carbapenem antibiotic. Since it is hydrolysed by dehydropeptidase-I, a zinc metallo-enzyme resident in the brush border of the renal tubule, it is co-administered with cilastatin, a reversible inhibitor of this ...
George L. Drusano
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Insertion Sequence Transposition Determines Imipenem Resistance in Acinetobacter baumannii
This study employed genomewide analysis to investigate potential resistance mechanisms in Acinetobacter baumannii following imipenem exposure. Imipenem-selected mutants were generated from the imipenem-susceptible strain ATCC 17978 by multistep selection
Kuo, Han-Yueh;Chang, Kai-Chih;Liu, Chih-Chin;Tang, Chuan Yi;Peng, Jhih-Hua;Lu, Chia-Wei;Tu, Chi-Chao;Liou, Ming-Li +1 more
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Comparative study of imipenem in severe infections [PDF]
Forty patients with severe bacterial infections due to micro-organisms known or presumed to be sensitive to both study antibiotics, were randomized to receive either imipenem with cilastatin, 500 mg/500 mg iv tid (20 patients), or cefotaxime, 2 g iv tid (
Glauser, M. P., Baumgartner, J. D.
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Pharmacokinetics of imipenem in healthy volunteers
The pharmacokinetics of imipenem were evaluated in four studies involving 49 healthy men, several of whom participated in more than one study. Within a dose-range of 150 to 1000 mg, imipenem was found to give high plasma concentrations, proportional to ...
Barbro Bjornegard +3 more
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Imipenem/cilastatin use in newborn infants Yenidogan doneminde imipenem/silastatin kullanimi
In our study we evaluated the safety of using imipenem/cilastin during the neonatal period. The cases which were treated with imipenem/cilastin because of sepsis and/or pneumonia were included in this study.
Iiter, O. +5 more
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the article presents the results of a retrospective study conducted in the period from 2008 to 2011 in Moscow’s hospitals. The aim of the study was to compare the clinical and pharmacoeconomical efficacy of carbapenems in nosocomial pneumonia treatment ...
I. I. Shteynberg +2 more
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Comparative imipenem treatment of Staphylococcus aureus endocarditis in the rat.
The efficacy of imipenem alone or in association with gentamicin against Staphylococcus aureus experimental endocarditis was compared to the efficacy of cloxacillin alone or in association with gentamicin.
Baumgartner, J.D., Glauser, M.P.
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Efficacy of imipenem/cilastatin in endocarditis
Imipenem, a potent new beta-lactam antibiotic, which is bactericidal against most pathogenic bacteria, and cilastatin, a dehydropeptidase inhibitor combined with imipenem to prevent the metabolism of imipenem in the kidney, were evaluated in the ...
Arcey, Sergio +4 more
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Imipenem stability in a predried susceptibility panel
We performed a 15-month study using 11 clinical strains and 1 control strain (ATCC 27853) of Pseudomonas aeruginosa to determine whether changes in the manufacturing process of Sensititre predried panels result in a reliable test of susceptibility to ...
Soja, Don T. +4 more
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