The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K +11 more
core +3 more sources
Identification, Genotyping and Antimicrobial Susceptibility Testing of Brucella spp. Isolated from Livestock in Egypt [PDF]
Brucellosis is a highly contagious zoonosis worldwide with economic and public health impacts. The aim of the present study was to identify Brucella (B.) spp. isolated from animal populations located in different districts of Egypt and to determine their
El-Adawy, Hosny +9 more
core +1 more source
The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M. +10 more
core +1 more source
First time identification of Pandoraea sputorum from a patient with cystic fibrosis in Argentina: a case report [PDF]
Background: Pandoraea species are considered emerging pathogens in the context of cystic fibrosis (CF) and are difficult to identify by conventional biochemical methods. These multidrug resistant bacteria remain poorly understood particularly in terms of
Alvarez, Florencia +11 more
core +2 more sources
The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé +95 more
core +1 more source
Gram-negative bacteria belonging to the Enterobacter cloacae complex are increasingly implicated in difficult-to-treat nosocomial infections, as exemplified by a recently characterized highly carbapenem-resistant clinical Enterobacter roggenkampii ...
Suruchi Nepal +7 more
doaj +1 more source
Treatment of multidrug resistant bacterial infections has been a great challenge globally. Previous studies including our study have highlighted the use of celecoxib, a non-steroidal anti-inflammatory drug in combination with antibiotic has decreased the
Madhavi Annamanedi +3 more
doaj +1 more source
Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina +15 more
core +2 more sources
Antibiotic resistance is a major Public Health challenge worldwide. Mechanisms other than resistance are described as contributors to therapeutic failure.
Celia Gil-Campillo +15 more
doaj +1 more source
Drug Utilization Evaluation of Imipenem and Assessing the Role of Pharmacist Interventions
Background and purpose: This study aimed at evaluating utilization of imipenem and assessing the role of pharmacist in rational use of antibiotics. Materials and methods: A retrospective/prospective observational study was conducted in Ramsar Imam Sajjad
Neda Farzadi +3 more
doaj

