Results 11 to 20 of about 65,673 (219)

Imipenem/Relebactam Ex Vivo Clearance during Continuous Renal Replacement Therapy

Antibiotics, 2021
(1) Purpose of this study: determination of adsorption and transmembrane clearances (CLTM) of imipenem and relebactam in ex vivo continuous hemofiltration (CH) and continuous hemodialysis (CHD) models.
Soo Min Jang, Lenar Yessayan, Michael Dean, Gabrielle Costello, Ravi Katwaru, Bruce A. Mueller   +5 more
doaj   +2 more sources

Toward Model-Informed Precision Dosing of Imipenem: Multicenter External Validation of Population Pharmacokinetic Models in Adult Critically Ill Patients [PDF]

Drug Design, Development and Therapy
Ping Zhang,1,2,* Xiaoping Pang,3,* Huadong Chen,4,* Jianping Zhu,1 Gang Liang,1 Yi Yang,1 Xuan Zhang,5 Zhenwei Yu1,21Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s ...
Zhang P, Pang X, Chen H, Zhu J, Liang G, Yang Y, Zhang X, Yu Z   +7 more
doaj   +2 more sources

Model-Informed Precision Dosing of Imipenem in an Obese Adolescent Patient with Augmented Renal Clearance and History of Schizophrenia

Infection and Drug Resistance
Yueliang Chen,1,* Yun Han,2,3,* Feng Guo,1 Zhenwei Yu2,3 1Intensive Care Unit, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Pharmacy, Sir Run Run Shaw Hospital,
Chen Y, Han Y, Guo F, Yu Z
doaj   +1 more source

Carbapenem resistance associated with coliuria among outpatient and hospitalised urology patients

New Microbes and New Infections, 2022
The World Health Organization in 2017 listed carbapenem resistant Enterobacteriaceae (CRE) with critical priority for research. A research to assess carbapenem resistant Escherichia coli (CREc) in coliuria among the outpatients and inpatients of a ...
A.A. Adegoke, W.E. Ikott, A.I. Okoh
doaj   +1 more source

Effect of Oxygen and Water on the Stability of Imipenem and Cilastatin Sodium for Injection

Pharmaceutical Fronts, 2022
The study aimed to investigate the factors affecting the stability of imipenem and cilastatin sodium for injection (IMI/CIL) to improve the quality and stability in IMI/CIL preparation.
Meng Zhang, Chun-Feng Liu, Xiao-Yan Chen, Li-Na Yang, Chun-Mei Zhu, Jian-Hao Teng, Hao-Xiang Wu, Fu-Li Zhang   +7 more
doaj   +1 more source

Primary Bacteremia Caused by Rhizobium radiobacter in Neonate: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2015
Rhizobium radiobacter is a gram-negative tumourigenic plant pathogen that rarely causes infections in humans. Rhizobium radiobacter has a strong predilection to cause infection particularly in those patients who have long standing indwelling foreign ...
Shreekant Tiwari, Siba Shanker Beriha
doaj   +1 more source

Aerobacterial Vaginosis among Women Attending an Infertility Clinic at a Tertiary Care Hospital in Chennai, India and Susceptibility Pattern of Isolates

Journal of Pure and Applied Microbiology, 2021
Genital infections and subsequent vaginosis diagnosed through high vaginal swab in women is caused due to fungi or bacteria. The presented study focused on determining the types, numbers and antibacterial susceptibility pattern of aerobic bacteria ...
Abigail R. Sopia, Pushpa Innocent D. Joseph, M. Kalyani, B. Ananthi, Suresh Dhanaraj, Allen John Henry   +5 more
doaj   +1 more source

Bacterial membrane vesicles from Acinetobacter baumannii induced by ceftazidime are more virulent than those induced by imipenem

Virulence, 2020
Patients with Acinetobacter baumannii bacteremia treated with antipseudomonal cephalosporins showed higher 14-day mortality than patients treated with antipseudomonal carbapenems.
Chun-Hsiang Chiu, Yi-Tzu Lee, Yu-Chun Lin, Shu-Chen Kuo, Ya-Sung Yang, Yung-Chih Wang, Yu-Han Liu, Jung-Chung Lin, Feng-Yee Chang, Te-Li Chen   +9 more
doaj   +1 more source

RESTORE-IMI 1: A Multicenter, Randomized, Doubleblind Trial Comparing Efficacy and Safety of Imipenem/Relebactam vs Colistin Plus Imipenem in Patients With Imipenem-nonsusceptible Bacterial Infections [PDF]

, 2020
Background. The β-lactamase inhibitor relebactam can restore imipenem activity against imipenem-nonsusceptible gram-negative pathogens. We evaluated imipenem/relebactam for treating imipenem-nonsusceptible infections. Methods.
Du, Jiejun, Joeng, Hee-Koung, Kaye, Keith S., Lyulko, Olexiy, Khan, Ireen, Stus, Viktor, Boucher, Helen W., Tipping, Robert W., Kartsonis, Nicholas A., Paschke, Amanda, Aggrey, Angela, Murta De Oliveira, Cláudia, File Jr, Thomas M., Brown, Michelle L., Young, Katherine, Motsch, Johann, Köksal, Iftihar, Butterton, Joan R.   +17 more
core   +1 more source

Methodology Establishment and Application of VITEK Mass Spectrometry to Detect Carbapenemase-Producing Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2022
The ability of VITEK mass spectrometry (MS) in detection of bacterial resistance is currently under exploration and evaluation. In this study, we developed and validated a VITEK MS method to rapidly test carbapenemase-producing Klebsiella pneumoniae ...
Haoyun Lin, Zhen Hu, Jinsong Wu, Yuemei Lu, Jine Chen, Wenyuan Wu   +5 more
doaj   +1 more source