Results 21 to 30 of about 65,673 (219)

Activity of imipenem/relebactam and comparators against KPC-producing Klebsiella pneumoniae and imipenem-resistant Pseudomonas aeruginosa

, 2023
Purpose: Relebactam is a novel β-lactamase inhibitor, which, when combined with imipenem/cilastatin, is active against both class A and class C β-lactamases.
Delgado Valverde, María Mercedes, Hidalgo, Carmen, Portillo Calderón, Inés María, Alcalde Rico, Manuel, Pascual Hernández, Álvaro, Conejo Gonzalo, Mª Carmen, Del Toro Esperón, Carlos   +6 more
core   +1 more source

Molecular detection of metallo-β-lactamase gene blaVIM-1 in imipenem-resistant Pseudomonas aeruginosa strains isolated from hospitalized patients in the hospitals of Isfahan

Advanced Biomedical Research, 2015
Background: Pseudomonas aeruginosa is an opportunistic human pathogen that causes serious problems, especially in people, who have immunodeficiency. In recent times, metallo-β-lactamase (MBLs) resistance in this bacterium has led to some difficulties in ...
Mansour Sedighi, Hamid Vaez, Mohsen Moghoofeie, Shima Hadifar, Golfam Oryan, Jamshid Faghri   +5 more
doaj   +1 more source

Syzygium aromaticum Extracts as a Potential Antibacterial Inhibitors against Clinical Isolates of Acinetobacter baumannii: An In-Silico-Supported In-Vitro Study

Antibiotics, 2021
Imipenem is the most efficient antibiotic against Acinetobacter baumannii infection, but new research has shown that the organism has also developed resistance to this agent. A.
Abdelhamed Mahmoud, Magdy M. Afifi, Fareed El Shenawy, Wesam Salem, Basem H. Elesawy   +4 more
doaj   +1 more source

Free Energy Decomposition of CarO Outer Membrane Protein of Acinetobacter baumannii

Cumhuriyet Science Journal, 2022
The increase in the number of antibiotic-resistant microorganisms reported today has made this issue one of the main topics of all institutes. Acineteobacter baumanni is a species that is on the list of the WHO and plays an important role, especially in ...
Emrah Sarıyer
doaj   +1 more source

The Effects of Colistin on Imipenem MICs in OXA-48 Producing Klebsiella pneumoniae Isolates: An In Vitro Study

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: A new approach to carbapenem resistance-K. pneumoniae infections is to use combination drug therapies. However, little data are available about the effectiveness of the in vitro carbapenem plus colistin combination against oxacillinase-48 ...
Yücel DUMAN, Mehmet Sait TEKEREKOĞLU, Çiğdem KUZUCU, Yusuf YAKUPOĞULLARI   +3 more
doaj   +1 more source

In vitro activity of biapenem and other carbapenems against Russian clinical isolates of Pseudomonas aeruginosa, Acinetobacter spp., and Enterobacterales [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2021
Objective. To evaluate in vitro activity of biapenem and other clinically available carbapenems against Russian clinical isolates of Enterobacterales, Pseudomonas aeruginosa и Acinetobacter spp., including isolates with acquired fermentative mechanisms ...
Kozlov R.S., Azyzov I.S., Dekhnich A.V., Ivanchik N.V., Kuzmenkov A.Yu., Martinovich А.А., Mikotina A.V., Sukhorukova M.V., Trushin I.V., Edelstein M.V.   +9 more
doaj   +1 more source

Celecoxib Enhances the Efficacy of Low-Dose Antibiotic Treatment against Polymicrobial Sepsis in Mice and Clinical Isolates of ESKAPE Pathogens

Frontiers in Microbiology, 2017
Treatment of multidrug resistant bacterial infections has been a great challenge globally. Previous studies including our study have highlighted the use of celecoxib, a non-steroidal anti-inflammatory drug in combination with antibiotic has decreased the
Madhavi Annamanedi, Gajapati Y. N. Varma, K. Anuradha, Arunasree M. Kalle   +3 more
doaj   +1 more source

Upstream region of OprD mutations in imipenem-resistant and imipenem-sensitive Pseudomonas isolates

, 2021
The current study was aimed at investigating the prevalence of the mutations upstream of the oprD coding region and its promoters among imipenem-resistant and sensitive Pseudomonas aeruginosa isolated from educational hospitals in Yazd City, Iran.
Astani, A., Afkhami, H., Kiani, M., Rostami, S., Zarei, M., Khozani, N. R., Zandi, H., Eslami, G., Khaledi, M.   +8 more
core   +1 more source

Proteomic Charting of Imipenem Adaptive Responses in a Highly Carbapenem Resistant Clinical Enterobacter roggenkampii Isolate

Antibiotics, 2021
Gram-negative bacteria belonging to the Enterobacter cloacae complex are increasingly implicated in difficult-to-treat nosocomial infections, as exemplified by a recently characterized highly carbapenem-resistant clinical Enterobacter roggenkampii ...
Suruchi Nepal, Sandra Maaß, Stefano Grasso, Francis M. Cavallo, Jürgen Bartel, Dörte Becher, Erik Bathoorn, Jan Maarten van Dijl   +7 more
doaj   +1 more source

Imipenem/relebactam érzékenységi vizsgálat E-teszttel karbapenem rezisztens Pseudomonas aeruginosa által okozott fertőzésekben

, 2022
A multirezisztens baktériumok (MRK) megjelenése és elterjedése, valamint az infekciók szempontjából magas kockázatú betegek számának emelkedése világszerte egyre nagyobb problémát okoz az egészségügyben. Az utóbbi években felbukkantak a karbapenemekre (
Ráti, Szabina
core