Results 21 to 30 of about 61,036 (213)

Mechanisms of resistance to imipenem in imipenem-resistant, ampicillin-sensitive Enterococcus faecium [PDF]

, 2001
Enterococcus faecium has six penicillin-binding proteins (PBP), where PBP5 seems to be the main target for beta-lactam antibiotics. The PBP profiles of three imipenem-resistant, ampicillin-sensitive E.
Lund, B,, Jalakas, K, El, Amin N, Tjernlund, A,, Lundberg, C, Wretlind, B   +5 more
core   +1 more source

Celecoxib Enhances the Efficacy of Low-Dose Antibiotic Treatment against Polymicrobial Sepsis in Mice and Clinical Isolates of ESKAPE Pathogens

Frontiers in Microbiology, 2017
Treatment of multidrug resistant bacterial infections has been a great challenge globally. Previous studies including our study have highlighted the use of celecoxib, a non-steroidal anti-inflammatory drug in combination with antibiotic has decreased the
Madhavi Annamanedi, Gajapati Y. N. Varma, K. Anuradha, Arunasree M. Kalle   +3 more
doaj   +1 more source

Proteomic Charting of Imipenem Adaptive Responses in a Highly Carbapenem Resistant Clinical Enterobacter roggenkampii Isolate

Antibiotics, 2021
Gram-negative bacteria belonging to the Enterobacter cloacae complex are increasingly implicated in difficult-to-treat nosocomial infections, as exemplified by a recently characterized highly carbapenem-resistant clinical Enterobacter roggenkampii ...
Suruchi Nepal, Sandra Maaß, Stefano Grasso, Francis M. Cavallo, Jürgen Bartel, Dörte Becher, Erik Bathoorn, Jan Maarten van Dijl   +7 more
doaj   +1 more source

Human Vitreous Penetration of Imipenem [PDF]

, 1994
The purpose of this study was to determine imipenem concentrations in vitreous humor of non-infected human eyes. Ten patients undergoing vitrectomy were infused with a single dose of either 0.5g (5 patients) or 1g (5 patients) of imipenem.
J.L. Salomon, F. Denis, M. Mounier, J.P. Adenis   +3 more
core   +1 more source

Drug Utilization Evaluation of Imipenem and Assessing the Role of Pharmacist Interventions

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: This study aimed at evaluating utilization of imipenem and assessing the role of pharmacist in rational use of antibiotics. Materials and methods: A retrospective/prospective observational study was conducted in Ramsar Imam Sajjad
Neda Farzadi, Ebrahim Salehifar, Lotfollah Davoodi, Hamideh Abbaspour Kasgari   +3 more
doaj  

Imipenem heteroresistance but not tolerance in Haemophilus influenzae during chronic lung infection associated with chronic obstructive pulmonary disease

Frontiers in Microbiology, 2023
Antibiotic resistance is a major Public Health challenge worldwide. Mechanisms other than resistance are described as contributors to therapeutic failure.
Celia Gil-Campillo, Celia Gil-Campillo, Celia Gil-Campillo, Aida González-Díaz, Aida González-Díaz, Beatriz Rapún-Araiz, Beatriz Rapún-Araiz, Oihane Iriarte-Elizaintzin, Iris Elizalde-Gutiérrez, Ariadna Fernández-Calvet, María Lázaro-Díez, Sara Martí, Sara Martí, Junkal Garmendia, Junkal Garmendia, Junkal Garmendia   +15 more
doaj   +1 more source

Imipenem/Cilastatin: The First Carbapenem Antibiotic [PDF]

, 1985
Imipenem/cilastatin is the first of a new class of β-lactam antibiotics called carbapenems. The antibacterial spectrum of imipenem exceeds any antibiotic investigated to date and includes gram-positive, gram-negative, and anaerobic organisms.
Donald C. McLeod, James A. Lyon
core   +1 more source

MALDI-TOF MS analysis of imipenem. [PDF]

, 2012
(A) Imipenem and its natural degradation product. (B) Mass spectra of imipenem and its natural degradation product as determined using the Ultraflex mass spectrometer.
Abdelaziz Touati (184768), Jean-Michel Brunel (135062), Sofiane Bakour (184734), Marie Kempf (184731), Mourad Drissi (184753), Christophe Flaudrops (184739), Esma Mesli (184760), Meryem Berrazeg (184744), Jean-Marc Rolain (34775)   +8 more
core   +1 more source

Mortality rate in patients with nosocomial Acinetobacter meningitis from a Brazilian hospital

Brazilian Journal of Infectious Diseases
BACKGROUND: The mortality rate due to Acinetobacter baumannii nosocomial meningitis (ANM) is high. OBJECTIVE: The aim of this study was to evaluate the factors that have influence over the outcomes in ANM patients. METHODS: A retrospective analysis of 22
Felipe Francisco Tuon, Sergio R Penteado-Filho, Diogo Amarante, Marcio A Andrade, Luis A Borba   +4 more
doaj   +1 more source

Emergence of Carbapenem Resistant Non-Fermenting Gram-Negative Bacilli Isolated in an Icu of a Tertiary Care Hospital [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: The emergence and spread of Multi-Drug Resistant (MDR) Non-Fermenting Gram-Negative Bacilli (NFGNB) in Intensive Care Units (ICU) and their genetic potential to transmit diverse antibiotic resistance regardless of their ability to ...
Sonika Agarwal, Barnali Kakati, Sushant Khanduri, Shalini Gupta   +3 more
doaj   +1 more source